Nigerasperones a-c, new monomeric and dimeric naphtho-gamma-pyrones from a marine alga-derived endophytic fungus aspergillus niger en-13
文献类型：期刊论文
| 作者 | Zhang, Yi; Li, Xiao-Ming; Wang, Bin-Gui |
| 刊名 | Journal of antibiotics
 |
| 出版日期 | 2007-03-01 |
| 卷号 | 60期号:3页码:204-210 |
| 关键词 | Colpomenia sinuosa Algous endophytic fungus Aspergillus niger Naphtho-gamma-pyrone |
| ISSN号 | 0021-8820 |
| 通讯作者 | Li, xiao-ming() |
| 英文摘要 | Three new naphtho-gamma-pyrones, 5-hydroxy-6,8-dimethoxy-2-hydroxymethyl-4h-naphtho[2,3-b]pyran-4- one (1, nigerasperone a), 3,3'-dihydro-2,2',5,5'-tetrahydroxy-8,8', 10,10'-tetramethoxy-2,2'-dimethyl-(6',9-bi-4h-naphtho[1,2-b]pyran)-4,4'-dione (2, nigerasperone 13), and 3'-hydro-2',5,5',8-tetrahydroxy-6,6',8'-trimethoxy-2,2'- dimethyl-(7,10'-bi-4h-naphtho[2,3-b]pyran)-4,4'-dione (3, nigerasperone c), together with nine related known compounds were characterized from aspergillus niger en-13, an endophytic fungus isolated from the marine brown alga colpomenia sinuosa. their structures were elucidated by detailed analysis of spectroscopic data and by comparison with literature reports. in the cytotoxic assay, these compounds did not show remarkable inhibitory effects against a549 and smmc-7721 tumor cell lines. however, 3 and several known compounds showed weak antifungal activity against candida albicans and moderate activity on dpph scavenging. |
| WOS关键词 | METABOLITES ; FONSECAEUS ; AURASPERONE ; INHIBITORS |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy |
| WOS类目 | Biotechnology & Applied Microbiology ; Immunology ; Microbiology ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000245648800006 |
| 出版者 | JAPAN ANTIBIOTICS RESEARCH ASSOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2382413 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Li, Xiao-Ming |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Yi,Li, Xiao-Ming,Wang, Bin-Gui. Nigerasperones a-c, new monomeric and dimeric naphtho-gamma-pyrones from a marine alga-derived endophytic fungus aspergillus niger en-13[J]. Journal of antibiotics,2007,60(3):204-210. |
| APA | Zhang, Yi,Li, Xiao-Ming,&Wang, Bin-Gui.(2007).Nigerasperones a-c, new monomeric and dimeric naphtho-gamma-pyrones from a marine alga-derived endophytic fungus aspergillus niger en-13.Journal of antibiotics,60(3),204-210. |
| MLA | Zhang, Yi,et al."Nigerasperones a-c, new monomeric and dimeric naphtho-gamma-pyrones from a marine alga-derived endophytic fungus aspergillus niger en-13".Journal of antibiotics 60.3(2007):204-210. |
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来源：中国科学院大学
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