Involvement of the histone acetyltransferase athac1 in the regulation of flowering time via repression of flowering locus c in arabidopsis
文献类型：期刊论文
| 作者 | Deng, WeiWei; Liu, ChunYan; Pei, Yanxi; Deng, Xian; Niu, LiFang; Cao, XiaoFeng |
| 刊名 | Plant physiology
 |
| 出版日期 | 2007-04-01 |
| 卷号 | 143期号:4页码:1660-1668 |
| ISSN号 | 0032-0889 |
| DOI | 10.1104/pp.106.095521 |
| 通讯作者 | Cao, xiaofeng(xfcao@genetics.ac.cn) |
| 英文摘要 | Histone acetylation is an important posttranslational modification correlated with gene activation. in arabidopsis (arabidopsis thaliana), the histone acetyltransferase athac1 is homologous to animal p300/creb (camp-responsive element-binding protein)-binding proteins, which are the main histone acetyltransferases participating in many physiological processes, including proliferation, differentiation, and apoptosis. the functions of p300/creb-binding proteins in animals are well characterized, whereas little is known about the roles of athac1 in developmental control in arabidopsis. lesions in athac1 caused pleiotropic developmental defects, including delayed flowering, a shortened primary root, and partially reduced fertility. analysis of the molecular basis of late flowering in hac1 mutants showed that the hac1 plants respond normally to day length, gibberellic acid treatment, and vernalization. furthermore, the expression level of the flowering repressor flowering locus c (flc) is increased in hac1 mutants, indicating that the late-flowering phenotype of hac1 mutants is mediated by flc. since histone acetylation is usually associated with the activation of gene expression, histone modifications of flc chromatin are not affected by mutations in hac1 and expression levels of all known autonomous pathway genes are unchanged in hac1 plants, we propose that hac1 affects flowering time by epigenetic modification of factors upstream of flc. |
| WOS关键词 | MADS-BOX GENE ; WINTER-ANNUAL HABIT ; PLANT DEVELOPMENT ; TRANSCRIPTIONAL REGULATION ; CHROMATIN MODIFICATION ; FLORAL INITIATION ; BINDING PROTEIN ; VERNALIZATION ; THALIANA ; METHYLATION |
| WOS研究方向 | Plant Sciences |
| WOS类目 | Plant Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000245781000018 |
| 出版者 | AMER SOC PLANT BIOLOGISTS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2382497 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Cao, XiaoFeng |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Plant Genom, Inst Genet & Dev Biol, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Ctr Plant Gene Res, Inst Genet & Dev Biol, Beijing 100101, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 4.Shanxi Univ, Coll Life Sci & Technol, Taiyuan 030006, Peoples R China |
| 推荐引用方式 GB/T 7714 | Deng, WeiWei,Liu, ChunYan,Pei, Yanxi,et al. Involvement of the histone acetyltransferase athac1 in the regulation of flowering time via repression of flowering locus c in arabidopsis[J]. Plant physiology,2007,143(4):1660-1668. |
| APA | Deng, WeiWei,Liu, ChunYan,Pei, Yanxi,Deng, Xian,Niu, LiFang,&Cao, XiaoFeng.(2007).Involvement of the histone acetyltransferase athac1 in the regulation of flowering time via repression of flowering locus c in arabidopsis.Plant physiology,143(4),1660-1668. |
| MLA | Deng, WeiWei,et al."Involvement of the histone acetyltransferase athac1 in the regulation of flowering time via repression of flowering locus c in arabidopsis".Plant physiology 143.4(2007):1660-1668. |
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来源：中国科学院大学
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