Spectrofiuorimetric study on the weak interaction between atp and n-a-4-tosyl-l-arginine methyl ester hydrochloride
文献类型：期刊论文
| 作者 | Ma, Yan-Qing; Lue, Gong-Xuan; Li, Ying; Liu, Shu-Hua; Xian, Liang |
| 刊名 | Chinese journal of chemistry
 |
| 出版日期 | 2007-09-01 |
| 卷号 | 25期号:9页码:1253-1258 |
| 关键词 | N-a-4-tosyl-l-arginine methyl ester hydrochloride Adenosine-5'-triphosphate (atp) Binding site Fluorescence quenching Fourier transform infrared (ft-ir) spectra |
| ISSN号 | 1001-604X |
| 通讯作者 | Ma, yan-qing() |
| 英文摘要 | In this paper, some new results on the selective weak interaction between n-alpha-4-tosyl-l-arginine methyl ester hydrochloride (tame) and adenosine-5'-triphosphate (atp) have been reported. fluorescence spectrophotometry and fourier transform infrared (ft-ir) spectroscopy were used to investigate this kind of weak interaction. in fluorescence experiments, obvious fluorescence quenching phenomena were observed when tame was added, which indicated the weak interactions between tame and atp. it has been identified by fluorescence titration experiments that tame exhibited high selectivity to atp over adp and amp. ft-ir spectral results showed that an atp-tame adduct was formed. the experimental results indicated that the interaction sites were the guanidinium group of tame main-chain and the gamma-phosphate group of atp, and the interaction took place through hydrogen bonding and electrostatic force. in addition, the effects of metal ions on the weak interaction between atp and tame, or between atp and analogues of l-arginine were studied. |
| WOS关键词 | BINDING CHANGE MECHANISM ; HUMAN SERUM-ALBUMIN ; ADENOSINE 5'-TRIPHOSPHATE ; NUCLEOTIDE-BINDING ; FLUORESCENCE ; HYDROLYSIS ; RECEPTOR ; RECOGNITION ; F-1-ATPASE ; SYNTHASE |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000249473600007 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2383001 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Ma, Yan-Qing |
| 作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synthesis & Select Oxidat, Lanzhou 730000, Peoples R China 2.Grad Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Lanzhou Univ, Dept Chem, Lanzhou 730000, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ma, Yan-Qing,Lue, Gong-Xuan,Li, Ying,et al. Spectrofiuorimetric study on the weak interaction between atp and n-a-4-tosyl-l-arginine methyl ester hydrochloride[J]. Chinese journal of chemistry,2007,25(9):1253-1258. |
| APA | Ma, Yan-Qing,Lue, Gong-Xuan,Li, Ying,Liu, Shu-Hua,&Xian, Liang.(2007).Spectrofiuorimetric study on the weak interaction between atp and n-a-4-tosyl-l-arginine methyl ester hydrochloride.Chinese journal of chemistry,25(9),1253-1258. |
| MLA | Ma, Yan-Qing,et al."Spectrofiuorimetric study on the weak interaction between atp and n-a-4-tosyl-l-arginine methyl ester hydrochloride".Chinese journal of chemistry 25.9(2007):1253-1258. |
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来源：中国科学院大学
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