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Antimicrobial polyethylene with controlled copper release

文献类型:期刊论文

作者Zhang, Wei; Zhang, Yihe; Ji, Junhui; Yan, Qing; Huang, Anping; Chul, Paul K.
刊名Journal of biomedical materials research part a
出版日期2007-12-01
卷号83a期号:3页码:838-844
关键词Antimicrobial Plasma immersion ion implantation Copper Polyethylene
ISSN号1549-3296
DOI10.1002/jbm.a.31436
通讯作者Chul, paul k.(paul.chu@cityu.edu.hk)
英文摘要Good antiinfection properties of medical polymers, especially those used in artificial organs, are crucial to the minimization of microbial attack in nosocomial treatments. however, medical polymers fabricated by conventional methods usually have unstable and short-lived antimicrobial effects because of unsteady out-diffusion of the antibacterial species from the organic matrix. here, we introduce a dual plasma implantation process to enhance the properties. an inorganic antibacterial element, copper, is introduced into a medical polymer, polyethylene (pe), by means of copper plasma immersion ion implantation (piii) and a subsequent nitrogen piii process is used to regulate the release of the implanted cu. x-ray photoelectron spectroscopy and transmission electron microscopy reveal that a relatively large amount of copper of about 11% is implanted into pe to a depth of several hundred nanometers. chemical analyses confirm that the implanted cu does not bond with the polymer matrix. however, the n-2 plasma treatment produces various functional bonds such as c = n, and c = n which exert appreciable influence on regulating the out-diffusion rate of copper. the large amount of embedded cu, coupled with controlled release of the element to the surface, gives rise to excellent and long-lasting surface antibacterial properties of the plasma-treated polymer. the capability of controlling the release and storing the antibacterial reagent in a buried layer leads to better antimicrobial polymeric materials for medicine. (c) 2007 wiley periodicals, inc.
WOS关键词IMMERSION ION-IMPLANTATION ; POLY VINYL-CHLORIDE ; BACTERIAL ADHESION ; SURFACE MODIFICATION ; TEREPHTHALATE ; INFECTIONS ; MECHANISMS ; RESISTANCE ; CATHETER ; ENERGY
WOS研究方向Engineering ; Materials Science
WOS类目Engineering, Biomedical ; Materials Science, Biomaterials
语种英语
WOS记录号WOS:000250742700030
出版者WILEY-LISS
URI标识http://www.irgrid.ac.cn/handle/1471x/2383125
专题中国科学院大学
通讯作者Chul, Paul K.
作者单位1.City Univ Hong Kong, Dept Phys & Mat Sci, Kowloon, Hong Kong, Peoples R China
2.Chinese Acad Sci, Tech Inst Phys & Chem, Beijing 100080, Peoples R China
3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
4.China Univ Geosci, Sch Mat Sci & Technol, Beijing 100083, Peoples R China
推荐引用方式
GB/T 7714
Zhang, Wei,Zhang, Yihe,Ji, Junhui,et al. Antimicrobial polyethylene with controlled copper release[J]. Journal of biomedical materials research part a,2007,83a(3):838-844.
APA Zhang, Wei,Zhang, Yihe,Ji, Junhui,Yan, Qing,Huang, Anping,&Chul, Paul K..(2007).Antimicrobial polyethylene with controlled copper release.Journal of biomedical materials research part a,83a(3),838-844.
MLA Zhang, Wei,et al."Antimicrobial polyethylene with controlled copper release".Journal of biomedical materials research part a 83a.3(2007):838-844.

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来源:中国科学院大学

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