Leafy cotyledon1 is a key regulator of fatty acid biosynthesis in arabidopsis
文献类型：期刊论文
| 作者 | Mu, Jinye1,2,3; Tan, Helin1,2,3; Zheng, Qi1,2,3; Fu, Fuyou1,2; Liang, Yan1,2; Zhang, Jian1,2; Yang, Xiaohui1,2; Wang, Tai4; Chong, Kang4; Wang, Xiu-Jie1,2 |
| 刊名 | Plant physiology
 |
| 出版日期 | 2008-10-01 |
| 卷号 | 148期号:2页码:1042-1054 |
| ISSN号 | 0032-0889 |
| DOI | 10.1104/pp.108.126342 |
| 通讯作者 | Zuo, jianru(jrzuo@genetics.ac.cn) |
| 英文摘要 | In plants, fatty acids are de novo synthesized predominantly in plastids from acetyl-coenzyme a. although fatty acid biosynthesis has been biochemically well studied, little is known about the regulatory mechanisms of the pathway. here, we show that overexpression of the arabidopsis (arabidopsis thaliana) leafy cotyledon1 (lec1) gene causes globally increased expression of fatty acid biosynthetic genes, which are involved in key reactions of condensation, chain elongation, and desaturation of fatty acid biosynthesis. in the plastidial fatty acid synthetic pathway, over 58% of known enzyme-coding genes are up-regulated in lec1-overexpressing transgenic plants, including those encoding three subunits of acetyl-coenzyme a carboxylase, a key enzyme controlling the fatty acid biosynthesis flux. moreover, genes involved in glycolysis and lipid accumulation are also up-regulated. consistent with these results, levels of major fatty acid species and lipids were substantially increased in the transgenic plants. genetic analysis indicates that the lec1 function is partially dependent on abscisic acid insensitive3, fusca3, and wrinkled1 in the regulation of fatty acid biosynthesis. moreover, a similar phenotype was observed in transgenic arabidopsis plants overexpressing two lec1-like genes of brassica napus. these results suggest that lec1 and lec1-like genes act as key regulators to coordinate the expression of fatty acid biosynthetic genes, thereby representing promising targets for genetic improvement of oil production plants. |
| WOS关键词 | PLASTIDIC PYRUVATE-KINASE ; STORAGE PROTEIN GENES ; SEED OIL BIOSYNTHESIS ; EMBRYO DEVELOPMENT ; ABSCISIC-ACID ; GLUCOSE-6-PHOSPHATE DEHYDROGENASES ; TRANSCRIPTION FACTOR ; LIPID BIOSYNTHESIS ; TRANSGENIC PLANTS ; IN-PLANTA |
| WOS研究方向 | Plant Sciences |
| WOS类目 | Plant Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000259810400030 |
| 出版者 | AMER SOC PLANT BIOLOGISTS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2384422 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zuo, Jianru |
| 作者单位 | 1.Chinese Acad Sci, Inst Genet & Dev Biol, State Key Lab Plant Genom, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Inst Genet & Dev Biol, Natl Plant Gene Res Ctr, Beijing 100101, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Inst Bot, Beijing 100093, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mu, Jinye,Tan, Helin,Zheng, Qi,et al. Leafy cotyledon1 is a key regulator of fatty acid biosynthesis in arabidopsis[J]. Plant physiology,2008,148(2):1042-1054. |
| APA | Mu, Jinye.,Tan, Helin.,Zheng, Qi.,Fu, Fuyou.,Liang, Yan.,...&Zuo, Jianru.(2008).Leafy cotyledon1 is a key regulator of fatty acid biosynthesis in arabidopsis.Plant physiology,148(2),1042-1054. |
| MLA | Mu, Jinye,et al."Leafy cotyledon1 is a key regulator of fatty acid biosynthesis in arabidopsis".Plant physiology 148.2(2008):1042-1054. |
入库方式： iSwitch采集
来源：中国科学院大学
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。