Protein disulfide bond determination and its analysis by mass spectrometry
文献类型：期刊论文
| 作者 | Qiu Xiaoyan1,2; Cui Meng1; Liu Zhiqiang1; Liu Shuying1 |
| 刊名 | Progress in chemistry
 |
| 出版日期 | 2008-06-01 |
| 卷号 | 20期号:6页码:975-983 |
| 关键词 | Assignment of disulfide bond Mass spectrometry Ms/ms Tcep Stable isotope labeling |
| ISSN号 | 1005-281X |
| 通讯作者 | Qiu xiaoyan() |
| 英文摘要 | Disulfide bonds are one of the most common covalent posttranslational modifications of proteins. they play an important role in maintaining the three-dimensional structures of proteins and their biological activities. therefore, the determination of disulfide bonds becomes an important aspect for obtaining a comprehensive understanding of the chemical structure of a protein. numerous experimental methods have been developed for the determination of disulfide bonds in proteins. modern mass spectrometry has developed as an important tool for the analysis of disulfide bond patterns due to its advantages of being simple, rapid and sensitive. some useful methods for assignment of disulfide bonds in proteins are introduced, the developments and applications of mass spectrometry in this area are reviewed. |
| WOS关键词 | LASER-DESORPTION IONIZATION ; FAST-ATOM-BOMBARDMENT ; SPIDER SELENOCOSMIA-HUWENA ; N-GLYCOSYLATION SITES ; PEPTIDYL-LYS METALLOENDOPEPTIDASE ; ELECTRON-CAPTURE DISSOCIATION ; QUADRUPOLE COLLISION CELL ; ALPHA-AMYLASE INHIBITOR ; CROSS-LINKED PEPTIDES ; S-S BRIDGES |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000258749400021 |
| 出版者 | CHINESE ACAD SCIENCES |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2384840 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Qiu Xiaoyan |
| 作者单位 | 1.Chinese Acad Sci, Changchun Ctr Mass Spectrometry, Changchun Inst Appl Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qiu Xiaoyan,Cui Meng,Liu Zhiqiang,et al. Protein disulfide bond determination and its analysis by mass spectrometry[J]. Progress in chemistry,2008,20(6):975-983. |
| APA | Qiu Xiaoyan,Cui Meng,Liu Zhiqiang,&Liu Shuying.(2008).Protein disulfide bond determination and its analysis by mass spectrometry.Progress in chemistry,20(6),975-983. |
| MLA | Qiu Xiaoyan,et al."Protein disulfide bond determination and its analysis by mass spectrometry".Progress in chemistry 20.6(2008):975-983. |
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来源：中国科学院大学
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