Synthesis of phosphodiester-type nicotinamide adenine dinucleotide analogs
文献类型：期刊论文
| 作者 | Liu, Wujun1,2; Wu, Siguo1,2; Hou, Shuhua1,2; Zhao, Zongbao (Kent)1,3 |
| 刊名 | tetrahedron
 |
| 出版日期 | 2009-10-03 |
| 卷号 | 65期号:40页码:8378-8383 |
| 关键词 | Nicotinamide adenine dinucleotide Coupling reaction Phosphodiesters Bioorganic chemistry |
| 产权排序 | 1;1 |
| 通讯作者 | 赵宗保 |
| 英文摘要 | fourteen phosphodiester-type beta-nicotinamide adenine dinucleotide (nad+) analogs were prepared starting from nicotinamide. the phosphodiester linkage was effectively assembled in 69-93% yields via condensation reaction between 2'.3'-di-o-acetyl nicotinamide mononucleotide and alcohols in the presence of 2,4,6-triisopropylbenzenesulfonyl chloride. the analog beta-nicotinamide ribose-5-(2-phenylethyl) phosphate showed beneficial effects on cell growth of model microorganisms. (c) 2009 elsevier ltd. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, organic |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | cyclic adp-ribose ; mammalian-cells ; 1,4-nadh derivatives ; chemical-synthesis ; h-phosphonates ; nad ; agents ; chemistry ; phosphate ; strategy |
| 收录类别 | SCI ; IC |
| 原文出处 | false |
| 语种 | 英语 |
| WOS记录号 | WOS:000269995900010 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/102545]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Dalian Natl Lab Clean Energy, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Wujun,Wu, Siguo,Hou, Shuhua,et al. Synthesis of phosphodiester-type nicotinamide adenine dinucleotide analogs[J]. tetrahedron,2009,65(40):8378-8383. |
| APA | Liu, Wujun,Wu, Siguo,Hou, Shuhua,&Zhao, Zongbao .(2009).Synthesis of phosphodiester-type nicotinamide adenine dinucleotide analogs.tetrahedron,65(40),8378-8383. |
| MLA | Liu, Wujun,et al."Synthesis of phosphodiester-type nicotinamide adenine dinucleotide analogs".tetrahedron 65.40(2009):8378-8383. |
入库方式： OAI收割
来源：大连化学物理研究所
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