Synthesis and Application of Prenyl-Derived Photoaffinity Probes
文献类型：期刊论文
| 作者 | Li Lingdong1,2; Tang Wei1,2; Zhao Zongbao1 |
| 刊名 | chinese journal of chemistry
 |
| 出版日期 | 2009-07-01 |
| 卷号 | 27期号:7页码:1391-1396 |
| 关键词 | isoprenoid chain chemical probe photoaffinity labeling click chemistry chemical proteomics |
| 产权排序 | 1;1 |
| 通讯作者 | 赵宗保 |
| 英文摘要 | three photoaffinity probes containing isoprenoid chains and an azide group were synthesized using one-pot coupling reaction as the key step. the capability of these probes as labeling agents for isoprenoid chain-interacting proteins from saccharomyces cerevisiae proteome was validated by photoaffinity reaction and "click" conjunction with the biotin reporter followed by streptavidin blot analysis. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, multidisciplinary |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | geranylgeranyltransferase type-i ; histone deacetylase complexes ; protein farnesyltransferase ; farnesyl transferase ; diphosphate analogs ; esters ; prenyltransferases ; cycloaddition ; biochemistry ; inhibitors |
| 收录类别 | SCI ; IC |
| 原文出处 | false |
| 语种 | 英语 |
| WOS记录号 | WOS:000268625200031 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/102571]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian 116023, Liaoning, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li Lingdong,Tang Wei,Zhao Zongbao. Synthesis and Application of Prenyl-Derived Photoaffinity Probes[J]. chinese journal of chemistry,2009,27(7):1391-1396. |
| APA | Li Lingdong,Tang Wei,&Zhao Zongbao.(2009).Synthesis and Application of Prenyl-Derived Photoaffinity Probes.chinese journal of chemistry,27(7),1391-1396. |
| MLA | Li Lingdong,et al."Synthesis and Application of Prenyl-Derived Photoaffinity Probes".chinese journal of chemistry 27.7(2009):1391-1396. |
入库方式： OAI收割
来源：大连化学物理研究所
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