Fingerprint analysis of Ligusticum chuanxiong using hydrophilic interaction chromatography and reversed-phase liquid chromatography
文献类型：期刊论文
| 作者 | Jin, Yu1; Liang, Tu1; Fu, Qing1; Xiao, Yuan-Sheng1; Feng, Jia-Tao1; Ke, Yan-Xiong2; Liang, Xin-Miao1,2 |
| 刊名 | journal of chromatography a
 |
| 出版日期 | 2009-03-13 |
| 卷号 | 1216期号:11页码:2136-2141 |
| 关键词 | Fingerprint analysis Quality control Ligusticum chuanxiong Hydrophilic interaction chromatography (HILIC) Reversed-phase liquid chromatography (RPLC) Polar compounds |
| 产权排序 | 1;1 |
| 通讯作者 | 梁鑫淼 |
| 英文摘要 | fingerprint analysis is considered one of the most powerful approaches to quality control in traditional chinese medicines (tcms). in this study, a binary chromatographic fingerprint analysis was developed using hydrophilic interaction chromatography (hilic) and reversed-phase liquid chromatography (rplc) to gain more chemical information about polar compounds and weakly polar compounds. this method was used to construct a chromatographic fingerprint of ligusticum chuanxiong. the two chromatographic methods demonstrated good precision, reproducibility, and stability, with relative standard deviations of <2% for retention time and 7% for peak area for both hilic and rplc separations. data from the analysis of 14 samples by hilic and rplc were processed with similarity analysis, with correlation coefficients and congruence coefficients. this binary fingerprint analysis, using two chromatographic modes, is a powerful tool for characterizing the quality of samples, and can be used for the comprehensive quality control of tcms. (c) 2008 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences |
| 类目[WOS] | biochemical research methods ; chemistry, analytical |
| 研究领域[WOS] | biochemistry & molecular biology ; chemistry |
| 关键词[WOS] | electrospray mass-spectrometry ; diode-array detection ; quality-control ; polar compounds ; medicinal-plants ; herbal medicines ; hplc ; rhizoma ; dad ; identification |
| 收录类别 | SCI |
| 原文出处 | false |
| 语种 | 英语 |
| WOS记录号 | WOS:000264226500021 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/102577]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Grad Sch, Dalian 116023, Peoples R China 2.E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jin, Yu,Liang, Tu,Fu, Qing,et al. Fingerprint analysis of Ligusticum chuanxiong using hydrophilic interaction chromatography and reversed-phase liquid chromatography[J]. journal of chromatography a,2009,1216(11):2136-2141. |
| APA | Jin, Yu.,Liang, Tu.,Fu, Qing.,Xiao, Yuan-Sheng.,Feng, Jia-Tao.,...&Liang, Xin-Miao.(2009).Fingerprint analysis of Ligusticum chuanxiong using hydrophilic interaction chromatography and reversed-phase liquid chromatography.journal of chromatography a,1216(11),2136-2141. |
| MLA | Jin, Yu,et al."Fingerprint analysis of Ligusticum chuanxiong using hydrophilic interaction chromatography and reversed-phase liquid chromatography".journal of chromatography a 1216.11(2009):2136-2141. |
入库方式： OAI收割
来源：大连化学物理研究所
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