Characterization of polymethoxylated flavones in Fructus aurantii by off-line two-dimensional liquid chromatography/electrospray ionization-ion trap mass spectrometry
文献类型：期刊论文
| 作者 | Zhou, Da-Yong2; Xu, Qing1; Xue, Xing-Ya1; Zhang, Fei-Fang1; Liang, Xin-Miao1 |
| 刊名 | journal of pharmaceutical and biomedical analysis
 |
| 出版日期 | 2009-02-20 |
| 卷号 | 49期号:2页码:207-213 |
| 关键词 | 2D-LC ESI-ITMS Fructus aurantii Matrix effects Polymethoxylated flavones |
| 产权排序 | 2;2 |
| 通讯作者 | 梁鑫淼 |
| 英文摘要 | off-line two-dimensional reversed-phase liquid chromatography (2d-rplc) coupled to electrospray ionization-ion trap mass spectrometry (esi-itms) was operated in positive mode (pi) to characterize polymethoxylated flavonoids (pmfs) in botanical sample. the fragments of [m+h-nx15](+) produced by loss of one or more methyl group from the protonated molecules, as well as [m+h-14](+), [m+h-29](+), [m+h-33](+), [m+h-43](+), [m+h-46](+) and [m+h-61](+) fragments formed the multiple ms (ms(n)) "fingerprint" of pmfs. 42 target compounds were tentatively identified from the extract of fructus aurantii (f. aurontii) based on this "fingerprint". experimental outcomes indicated that the application of 2d separation method can reduce the matrix suppression of analytes caused by the coelution with interferential components and the column overloading of interferential components. 42 versus 23 target compounds were detected through 2d versus 1 d method, which confirm the superiority of 2d coupled to ms in elimination of matrix effects. (c) 2008 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; physical sciences ; life sciences & biomedicine |
| 类目[WOS] | chemistry, analytical ; pharmacology & pharmacy |
| 研究领域[WOS] | chemistry ; pharmacology & pharmacy |
| 关键词[WOS] | traditional chinese medicines ; separation ; performance ; lc ; identification ; integration ; ms |
| 收录类别 | SCI |
| 原文出处 | false |
| 语种 | 英语 |
| WOS记录号 | WOS:000263434900005 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/102679]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 2.Dalian Polytech Univ, Coll Bio & Food Technol, Dalian 116034, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Da-Yong,Xu, Qing,Xue, Xing-Ya,et al. Characterization of polymethoxylated flavones in Fructus aurantii by off-line two-dimensional liquid chromatography/electrospray ionization-ion trap mass spectrometry[J]. journal of pharmaceutical and biomedical analysis,2009,49(2):207-213. |
| APA | Zhou, Da-Yong,Xu, Qing,Xue, Xing-Ya,Zhang, Fei-Fang,&Liang, Xin-Miao.(2009).Characterization of polymethoxylated flavones in Fructus aurantii by off-line two-dimensional liquid chromatography/electrospray ionization-ion trap mass spectrometry.journal of pharmaceutical and biomedical analysis,49(2),207-213. |
| MLA | Zhou, Da-Yong,et al."Characterization of polymethoxylated flavones in Fructus aurantii by off-line two-dimensional liquid chromatography/electrospray ionization-ion trap mass spectrometry".journal of pharmaceutical and biomedical analysis 49.2(2009):207-213. |
入库方式： OAI收割
来源：大连化学物理研究所
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