Asymmetric reduction of substituted alpha- and beta-ketoesters by bacillus pumilus phe-c3
文献类型:期刊论文
作者 | He, Chunmao1,2; Chang, Dongliang1,3; Zhang, Jie3 |
刊名 | Tetrahedron-asymmetry
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出版日期 | 2008-06-16 |
卷号 | 19期号:11页码:1347-1351 |
ISSN号 | 0957-4166 |
DOI | 10.1016/j.tetasy.2008.05.003 |
通讯作者 | Chang, dongliang(chang@gic.ac.cn) |
英文摘要 | The enantioselective reduction of substituted alpha- and beta-ketoesters using resting cells of bacillus pumilus phe-c3 was investigated. effects of substrate concentration on the catalytic efficiency of the microorganism were studied. preparative scale productions were carried out under the optimized conditions with 62.4-91.0% yields and 90.2-97.1% ee. the cells retained 80% of initial activity after recycling for six times. (c) 2008 elsevier ltd. all rights reserved. |
WOS关键词 | HYDROXY ACID-ESTERS ; KINETIC RESOLUTION ; DIASTEREOSELECTIVE SYNTHESIS ; ABSOLUTE-CONFIGURATION ; STEREOCHEMICAL CONTROL ; CATALYZED RESOLUTION ; SECONDARY ALCOHOLS ; BAKERS-YEAST ; WHOLE CELLS ; LIPASE |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Inorganic & Nuclear ; Chemistry, Organic ; Chemistry, Physical |
语种 | 英语 |
WOS记录号 | WOS:000257811900009 |
出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2386757 |
专题 | 中国科学院大学 |
通讯作者 | Chang, Dongliang |
作者单位 | 1.Chinese Acad Sci, Guangzhou Inst Chem, Guangzhou 510650, Guangdong, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China 3.Chinese Acad Sci, Jiaxing Res Ctr Appl Chem, Jiaxing 314006, Peoples R China |
推荐引用方式 GB/T 7714 | He, Chunmao,Chang, Dongliang,Zhang, Jie. Asymmetric reduction of substituted alpha- and beta-ketoesters by bacillus pumilus phe-c3[J]. Tetrahedron-asymmetry,2008,19(11):1347-1351. |
APA | He, Chunmao,Chang, Dongliang,&Zhang, Jie.(2008).Asymmetric reduction of substituted alpha- and beta-ketoesters by bacillus pumilus phe-c3.Tetrahedron-asymmetry,19(11),1347-1351. |
MLA | He, Chunmao,et al."Asymmetric reduction of substituted alpha- and beta-ketoesters by bacillus pumilus phe-c3".Tetrahedron-asymmetry 19.11(2008):1347-1351. |
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来源:中国科学院大学
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