Preparation of polyamine-functionalized copper specific adsorbents for selective adsorption of copper
文献类型：期刊论文
| 作者 | Yu, Zhiyuan; Wu, Ren'an; Wu, Minghuo; Zhao, Liang; Li, Ruibin; Zou, Hanfa |
| 刊名 | colloids and surfaces b-biointerfaces
 |
| 出版日期 | 2010-07-01 |
| 卷号 | 78期号:2页码:222-228 |
| 关键词 | Microspheres Adsorbent Copper Wilson's disease Triethylenetetramine Tetraethylenepentamine |
| ISSN号 | 0927-7765 |
| 产权排序 | 1;1 |
| 通讯作者 | 邹汉法 |
| 英文摘要 | the level of serum free copper is greatly elevated in wilson's disease. for patients with acute wilson's disease, liver transplantation is the only lifesaving treatment. plasma exchange or albumin dialysis is often used as a bridge to liver transplantation to maintain a stable clinical status for patients. hemoperfusion is another effective therapy in removing toxins from the plasma. however, hemoperfusion has not been reported to remove copper due to lack of copper specific adsorbent. in this work, copper chelating agents, triethylenetetramine and tetraethylenepentamine, were covalently immobilized onto macroporous poly(glycidyl methacrylate-co-trimethylolpropane trimethacrylate) microspheres to prepare copper specific adsorbents. the resulting adsorbents demonstrated good adsorption capacities of 63.44 and 58.48 mg/g, respectively, for cu(2+) ion. additionally, with the interference of other metal ions such as fe(2+), mg(2+), zn(2+) and ca(2+), the prepared copper adsorbents still demonstrated good specificity toward cu(2+) ion. these results indicate that the adsorbents are promising adsorbents in hemoperfusion therapy for selective removal of copper for patients with severe wilson's disease. (c) 2010 elsevier b.v. all rights reserved. |
| WOS标题词 | science & technology ; life sciences & biomedicine ; physical sciences ; technology |
| 类目[WOS] | biophysics ; chemistry, physical ; materials science, biomaterials |
| 研究领域[WOS] | biophysics ; chemistry ; materials science |
| 关键词[WOS] | inorganic complex compounds ; human serum-albumin ; wilsons-disease ; liver-transplantation ; polydentate groups ; binding ; ion ; triethylenetetramine ; dialysis ; affinity |
| 收录类别 | SCI |
| 原文出处 | false |
| 语种 | 英语 |
| WOS记录号 | WOS:000278167100011 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/103135]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Zhiyuan,Wu, Ren'an,Wu, Minghuo,et al. Preparation of polyamine-functionalized copper specific adsorbents for selective adsorption of copper[J]. colloids and surfaces b-biointerfaces,2010,78(2):222-228. |
| APA | Yu, Zhiyuan,Wu, Ren'an,Wu, Minghuo,Zhao, Liang,Li, Ruibin,&Zou, Hanfa.(2010).Preparation of polyamine-functionalized copper specific adsorbents for selective adsorption of copper.colloids and surfaces b-biointerfaces,78(2),222-228. |
| MLA | Yu, Zhiyuan,et al."Preparation of polyamine-functionalized copper specific adsorbents for selective adsorption of copper".colloids and surfaces b-biointerfaces 78.2(2010):222-228. |
入库方式： OAI收割
来源：大连化学物理研究所
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