Polyhedral Oligomeric Silsesquioxane as a Cross-linker for Preparation of Inorganic-Organic Hybrid Monolithic Columns
文献类型：期刊论文
| 作者 | Wu, Minghuo1,2; Wu, Ren'an1; Li, Ruibing1,2; Qin, Hongqiang1,2; Dong, Jing1; Zhang, Zhenbin1,2; Zou, Hanfa1 |
| 刊名 | analytical chemistry
 |
| 出版日期 | 2010-07-01 |
| 卷号 | 82期号:13页码:5447-5454 |
| ISSN号 | 0003-2700 |
| 通讯作者 | 邹汉法 |
| 产权排序 | 1;1 |
| 英文摘要 | an inorganic-organic hybrid monolithic capillary column was synthesized via thermal free radical copolymerization within the confines of a capillary using a polyhedral oligomeric silsesquioxane (poss) reagent as the inorganic-organic hybrid cross-linker and a synthesized long carbon chain quaternary ammonium methacrylate of n-(2-(methacryloyloxy)ethyl)-dimethy-loctadecylammonium bromide (mdoab) as the organic monomer. the preparation process was as simple as pure organic polymer-based monolithic columns instead of using poss as the nanosized inorganic-organic hybrid blocks (cross-linker) of the monolithic matrix. the pore properties and permeability could be tuned by the composition of the polymerization mixture. the characterization and evaluation results indicated that the synthesized mdoa-poss hybrid monolith possessed the merits of organic polymer-based monoliths and silica-based monoliths with good mechanical and ph (ph 1-11) stabilities, which may be attributed to the incorporation of the rigid nanosized silica core of poss. column efficiencies of 223 000 and 50 000 n/m were observed in capillary electro-driven chromatography (cec) and mu-hplc, respectively. peptides and standard proteins were baseline separated by this hybrid column in cec and mu-hplc, respectively, as well. the separation of bovine serum albumin (bsa) tryptic digest was also attempted to show its potential application in proteome analysis. |
| WOS标题词 | science & technology ; physical sciences |
| 类目[WOS] | chemistry, analytical |
| 研究领域[WOS] | chemistry |
| 关键词[WOS] | performance liquid-chromatography ; capillary electrochromatography ; stationary phases ; silica capillaries ; separation ; polymers ; nanocomposites ; copolymers ; proteins ; monomer |
| 收录类别 | SCI |
| 原文出处 | false |
| 语种 | 英语 |
| WOS记录号 | WOS:000279253300010 |
| 公开日期 | 2010-11-30 |
| 源URL | [http://159.226.238.44/handle/321008/103143]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 作者单位 | 1.Chinese Acad Sci, Dalian Inst Chem Phys, Natl Chromatog R&A Ctr, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Minghuo,Wu, Ren'an,Li, Ruibing,et al. Polyhedral Oligomeric Silsesquioxane as a Cross-linker for Preparation of Inorganic-Organic Hybrid Monolithic Columns[J]. analytical chemistry,2010,82(13):5447-5454. |
| APA | Wu, Minghuo.,Wu, Ren'an.,Li, Ruibing.,Qin, Hongqiang.,Dong, Jing.,...&Zou, Hanfa.(2010).Polyhedral Oligomeric Silsesquioxane as a Cross-linker for Preparation of Inorganic-Organic Hybrid Monolithic Columns.analytical chemistry,82(13),5447-5454. |
| MLA | Wu, Minghuo,et al."Polyhedral Oligomeric Silsesquioxane as a Cross-linker for Preparation of Inorganic-Organic Hybrid Monolithic Columns".analytical chemistry 82.13(2010):5447-5454. |
入库方式： OAI收割
来源：大连化学物理研究所
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