Regulation of protein function: crystal packing interfaces and conformational dimerization
文献类型：期刊论文
| 作者 | Crowley, Peter B.1; Matias, Pedro M.2; Mi, Hualing3; Firbank, Susan J.4; Banfield, Mark J.4; Dennison, Christopher4 |
| 刊名 | Biochemistry
 |
| 出版日期 | 2008-06-24 |
| 卷号 | 47期号:25页码:6583-6589 |
| ISSN号 | 0006-2960 |
| DOI | 10.1021/bi800125h |
| 通讯作者 | Crowley, peter b.(peter.crowley@ucd.ie) |
| 英文摘要 | The accepted view of interprotein electron transport involves molecules diffusing between donor and acceptor redox sites. an emerging alternative hypothesis is that efficient long-range electron transport can be achieved through proteins arranged in supramolecular assemblies. in this study, we have investigated the crystal packing interfaces in three crystal forms of plastocyanin, an integral component of the photosynthetic electron transport chain, and discuss their potential relevance to in vivo supramolecular assemblies. symmetry-related protein chains within these crystals have cu-cu separations of <25 angstrom, a distance that readily supports electron transfer. in one structure, the plastocyanin molecule exists in two forms in which a backbone displacement coupled with side chain rearrangements enables the modulation of protein-protein interfaces. |
| WOS关键词 | CYANOBACTERIUM PHORMIDIUM-LAMINOSUM ; CATION-PI INTERACTIONS ; ELECTRON-TRANSFER ; CYTOCHROME-F ; PARACOCCUS-DENITRIFICANS ; BINDING-SITE ; IN-VIVO ; PLASTOCYANIN ; STATE ; CHLOROPLAST |
| WOS研究方向 | Biochemistry & Molecular Biology |
| WOS类目 | Biochemistry & Molecular Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000256852900007 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2388838 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Crowley, Peter B. |
| 作者单位 | 1.Univ Coll Dublin, Conway Inst, UCD Sch Biomol & Biomed Sci, Dublin 4, Ireland 2.Univ Nova Lisboa, Inst Tecnol Quim & Biol, P-2781901 Oeiras, Portugal 3.Chinese Acad Sci, Grad Sch, Shanghai Inst Biol Sci, Inst Plant Physiol & Ecol,Natl Lab Plant Mol Gene, Shanghai 200032, Peoples R China 4.Univ Newcastle, Sch Med, Inst Cell & Mol Biosci, Newcastle Upon Tyne NE2 4HH, Tyne & Wear, England |
| 推荐引用方式 GB/T 7714 | Crowley, Peter B.,Matias, Pedro M.,Mi, Hualing,et al. Regulation of protein function: crystal packing interfaces and conformational dimerization[J]. Biochemistry,2008,47(25):6583-6589. |
| APA | Crowley, Peter B.,Matias, Pedro M.,Mi, Hualing,Firbank, Susan J.,Banfield, Mark J.,&Dennison, Christopher.(2008).Regulation of protein function: crystal packing interfaces and conformational dimerization.Biochemistry,47(25),6583-6589. |
| MLA | Crowley, Peter B.,et al."Regulation of protein function: crystal packing interfaces and conformational dimerization".Biochemistry 47.25(2008):6583-6589. |
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来源：中国科学院大学
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