Genome-wide mapping of conserved micrornas and their host transcripts in tribolium castaneum
文献类型：期刊论文
| 作者 | Luo, Qibin1,2; Zhou, Qing2,3; Yu, Xiaomin2,3; Lin, Hongbin2,3; Hu, Songnian1,2; Yu, Jun1,2 |
| 刊名 | Journal of genetics and genomics
 |
| 出版日期 | 2008-06-01 |
| 卷号 | 35期号:6页码:349-355 |
| 关键词 | Mirna Host transcript Intronic mirna Tribolium castaneum |
| ISSN号 | 1673-8527 |
| 通讯作者 | Yu, jun(junyu@big.ac.cn) |
| 英文摘要 | Micrornas (mirnas) are endogenous 22-nt rnas, which play important regulatory roles by post-transcriptional gene silencing. a computational strategy has been developed for the identification of conserved mirnas based on features of known metazoan mirnas in red flour beetle (tribolium castaneum), which is regarded as one of the major laboratory models of arthropods. among 118 putative mirnas, 47% and 53% of the predicted mirnas from the red flour beetle are harbored by known protein-coding genes (intronic) and genes located outside (intergenic mirna), respectively. there are 31 intronic mirnas in the same transcriptional orientation as the host genes, which may share rna polymerase ii and spliceosomal machinery with their host genes for their biogenesis. a hypothetical feedback model has been proposed based on the analysis of the relationship between intronic mirnas and their host genes in the development of red flour beetle. |
| WOS关键词 | COMPUTATIONAL IDENTIFICATION ; CAENORHABDITIS-ELEGANS/ ; INTRONIC MICRORNAS ; TARGET GENES ; DROSOPHILA ; RNAS ; DIFFERENTIATION ; PREDICTION ; EVOLUTION ; HUNDREDS |
| WOS研究方向 | Biochemistry & Molecular Biology ; Genetics & Heredity |
| WOS类目 | Biochemistry & Molecular Biology ; Genetics & Heredity |
| 语种 | 英语 |
| WOS记录号 | WOS:000258273900005 |
| 出版者 | SCIENCE PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2388943 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Yu, Jun |
| 作者单位 | 1.Zhejiang Univ, James D Watson Inst Genome Sci, Hangzhou 310008, Zhejiang, Peoples R China 2.Chinese Acad Sci, Beijing Inst Genom, Key Lab Genome Informat & Sci, Beijing 100029, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Luo, Qibin,Zhou, Qing,Yu, Xiaomin,et al. Genome-wide mapping of conserved micrornas and their host transcripts in tribolium castaneum[J]. Journal of genetics and genomics,2008,35(6):349-355. |
| APA | Luo, Qibin,Zhou, Qing,Yu, Xiaomin,Lin, Hongbin,Hu, Songnian,&Yu, Jun.(2008).Genome-wide mapping of conserved micrornas and their host transcripts in tribolium castaneum.Journal of genetics and genomics,35(6),349-355. |
| MLA | Luo, Qibin,et al."Genome-wide mapping of conserved micrornas and their host transcripts in tribolium castaneum".Journal of genetics and genomics 35.6(2008):349-355. |
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来源：中国科学院大学
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