中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Tree of life based on genome context networks

文献类型:期刊论文

作者Ding, Guohui1,2; Yu, Zhonghao3; Zhao, Jing3,4; Wang, Zhen1,2; Li, Yun1,2; Xing, Xiaobin1,2; Wang, Chuan1; Liu, Lei1,4; Li, Yixue1,3,4
刊名Plos one
出版日期2008-10-09
卷号3期号:10页码:8
ISSN号1932-6203
DOI10.1371/journal.pone.0003357
通讯作者Ding, guohui()
英文摘要Efforts in phylogenomics have greatly improved our understanding of the backbone tree of life. however, due to the systematic error in sequence data, a sequence-based phylogenomic approach leads to well-resolved but statistically significant incongruence. thus, independent test of current phylogenetic knowledge is required. here, we have devised a distance-based strategy to reconstruct a highly resolved backbone tree of life, on the basis of the genome context networks of 195 fully sequenced representative species. along with strongly supporting the monophylies of three superkingdoms and most taxonomic sub-divisions, the derived tree also suggests some intriguing results, such as high g+c gram positive origin of bacteria, classification of symbiobacterium thermophilum and alcanivorax borkumensis in firmicutes. furthermore, simulation analyses indicate that addition of more gene relationships with high accuracy can greatly improve the resolution of the phylogenetic tree. our results demonstrate the feasibility of the reconstruction of highly resolved phylogenetic tree with extensible gene networks across all three domains of life. this strategy also implies that the relationships between the genes (gene network) can define what kind of species it is.
WOS研究方向Science & Technology - Other Topics
WOS类目Multidisciplinary Sciences
语种英语
WOS记录号WOS:000265114100003
出版者PUBLIC LIBRARY SCIENCE
URI标识http://www.irgrid.ac.cn/handle/1471x/2389739
专题中国科学院大学
通讯作者Ding, Guohui
作者单位1.Chinese Acad Sci, Shanghai Inst Biol Sci, Key Lab Syst Biol, Bioinformat Ctr, Shanghai, Peoples R China
2.Chinese Acad Sci, Grad Sch, Shanghai, Peoples R China
3.Shanghai Jiao Tong Univ, Coll Life Sci & Biotechnol, Shanghai, Peoples R China
4.Shanghai Ctr Bioinformat Technol, Shanghai, Peoples R China
推荐引用方式
GB/T 7714
Ding, Guohui,Yu, Zhonghao,Zhao, Jing,et al. Tree of life based on genome context networks[J]. Plos one,2008,3(10):8.
APA Ding, Guohui.,Yu, Zhonghao.,Zhao, Jing.,Wang, Zhen.,Li, Yun.,...&Li, Yixue.(2008).Tree of life based on genome context networks.Plos one,3(10),8.
MLA Ding, Guohui,et al."Tree of life based on genome context networks".Plos one 3.10(2008):8.

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来源:中国科学院大学

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