Anti-diabetic effects of cesium aqua (n,n '-ethylene(salicylideneiminato)-5-sulfonato) oxovanadium (iv) dihydrate in streptozotocin-induced diabetic rats
文献类型：期刊论文
| 作者 | Li, Ming1; Wei, Dan1; Ding, Wenjun1; Baruah, Bharat2; Crans, Debbie C.2 |
| 刊名 | Biological trace element research
 |
| 出版日期 | 2008-03-01 |
| 卷号 | 121期号:3页码:226-232 |
| 关键词 | Vo( salen-so3) Anti-diabetic effects Stz-induced diabetic rats |
| ISSN号 | 0163-4984 |
| DOI | 10.1007/s12011-007-8049-8 |
| 通讯作者 | Ding, wenjun(dingwj@gucas.ac.cn) |
| 英文摘要 | The study has been designed to investigate the anti-diabetic effects of cesium aqua (n,n'-ethylene (salicylideneiminato)-5-sulfonato) oxovanadium (iv) dihydrate (vo(salen-so3)), an organic vanadium compound, in streptozotocin-induced diabetic rats. vo(salen-so3) was orally administrated to diabetic rats at the dose of 0.3 mg/ml through drinking water for 24 days. blood glucose level was significantly declined, and oral glucose tolerance was improved after vo(salen-so3) treatment. moreover, liver and muscle glycogen concentrations were markedly increased in vo(salen-so3)-treated diabetic rats. on the other hand, aspartate amino transferase and blood urea nitrogen in serum were significantly decreased after treatment with vo(salen-so3). take together, these results suggested that vo(salen-so3) may be of potential value in the therapy of diabetic symptom and hyperglycemia-induced hepatic and renal dysfunction. |
| WOS关键词 | VANADYL SULFATE ; INSULIN ; BIS(MALTOLATO)OXOVANADIUM(IV) ; GLUCOKINASE ; GLUCOSE-6-PHOSPHATASE ; COMPLICATIONS ; METABOLISM ; CHEMISTRY ; COMPLEX ; TISSUES |
| WOS研究方向 | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| WOS类目 | Biochemistry & Molecular Biology ; Endocrinology & Metabolism |
| 语种 | 英语 |
| WOS记录号 | WOS:000253128100005 |
| 出版者 | HUMANA PRESS INC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2390785 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Ding, Wenjun |
| 作者单位 | 1.Chinese Acad Sci, Grad Univ, Coll Life Sci, Beijing 100049, Peoples R China 2.Colorado State Univ, Dept Chem, Ft Collins, CO 80523 USA |
| 推荐引用方式 GB/T 7714 | Li, Ming,Wei, Dan,Ding, Wenjun,et al. Anti-diabetic effects of cesium aqua (n,n '-ethylene(salicylideneiminato)-5-sulfonato) oxovanadium (iv) dihydrate in streptozotocin-induced diabetic rats[J]. Biological trace element research,2008,121(3):226-232. |
| APA | Li, Ming,Wei, Dan,Ding, Wenjun,Baruah, Bharat,&Crans, Debbie C..(2008).Anti-diabetic effects of cesium aqua (n,n '-ethylene(salicylideneiminato)-5-sulfonato) oxovanadium (iv) dihydrate in streptozotocin-induced diabetic rats.Biological trace element research,121(3),226-232. |
| MLA | Li, Ming,et al."Anti-diabetic effects of cesium aqua (n,n '-ethylene(salicylideneiminato)-5-sulfonato) oxovanadium (iv) dihydrate in streptozotocin-induced diabetic rats".Biological trace element research 121.3(2008):226-232. |
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来源：中国科学院大学
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