Comparative genomics of human-like schistosoma japonicum genes indicates a putative mechanism for host-parasite relationship
文献类型：期刊论文
| 作者 | Yu, Fudong1,2,3; Li, Yixue1,3; Liu, Lei1,3; Li, Yuanyuan1,3 |
| 刊名 | Genomics
 |
| 出版日期 | 2008-02-01 |
| 卷号 | 91期号:2页码:152-157 |
| 关键词 | Horizontal gene transfer Phylogenetic analysis Codon usage bias Host-parasite interaction |
| ISSN号 | 0888-7543 |
| DOI | 10.1016/j.ygeno.2007.10.006 |
| 通讯作者 | Liu, lei(leiliu@sibs.ac.cn) |
| 英文摘要 | Schistosoma japonicum causes schistosomiasis in humans and livestock in the asia-pacific region. we assembled more than 43,700 s. japonicum expressed sequence tags and conducted comparative genomic analyses between s. japonicum and its human host. some schistosome genes showed exceptionally high similarity in nucleotide sequence to their human homologues, of which five exhibited anomalous phylogeny and human codon usage bias. the most plausible explanation for their presence is horizontal gene transfer from host to parasite. functional evidence suggests that s. japonicum might exploit host endocrine and immune signals for cell development and maturation via these host-like genes. (c) 2007 elsevier inc. all rights reserved. |
| WOS关键词 | EVOLUTIONARY ; EUKARYOTES ; EXPRESSION ; CELLS |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Genetics & Heredity |
| WOS类目 | Biotechnology & Applied Microbiology ; Genetics & Heredity |
| 语种 | 英语 |
| WOS记录号 | WOS:000252944500004 |
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2391343 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Liu, Lei |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Bioinformat Ctr, Key Lab Syst Biol, Shanghai 200031, Peoples R China 2.Chinese Acad Sci, Grad Sch, Shanghai 200031, Peoples R China 3.Shanghai Ctr Bioinformat Technol, Shanghai 200235, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu, Fudong,Li, Yixue,Liu, Lei,et al. Comparative genomics of human-like schistosoma japonicum genes indicates a putative mechanism for host-parasite relationship[J]. Genomics,2008,91(2):152-157. |
| APA | Yu, Fudong,Li, Yixue,Liu, Lei,&Li, Yuanyuan.(2008).Comparative genomics of human-like schistosoma japonicum genes indicates a putative mechanism for host-parasite relationship.Genomics,91(2),152-157. |
| MLA | Yu, Fudong,et al."Comparative genomics of human-like schistosoma japonicum genes indicates a putative mechanism for host-parasite relationship".Genomics 91.2(2008):152-157. |
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来源：中国科学院大学
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