Synthesis of cyclofenil rhenium tricarbonyl conjugates
文献类型:期刊论文
作者 | Zhu Hua1,2; Huang Liliang1,2; Zhang Chunchun1,2; Xu Jia1; Shen Yumei1 |
刊名 | Chinese journal of organic chemistry
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出版日期 | 2009-09-01 |
卷号 | 29期号:9页码:1450-1456 |
关键词 | Cyclofenil Rhenium tricarbonyl Breast cancer |
ISSN号 | 0253-2786 |
通讯作者 | Zhu hua() |
英文摘要 | Starting from 4,4'-dihydroxybenzophenone, three kinds of cyclofenil analogues were prepared by mcmurry coupling. under optimized conditions a series of cyclofenil rhenium(i) tricarbonyl conjugates were prepared as molecular probe precursors of estrogen receptor beta by omega-bromoalkylation and subsequent nucleophilic substitution. the study provides a useful assessment of the stage of the breast cancer by imaging er beta with the spect (single photon emission computed tomography) technique. the structures of final products and the intermediates were confirmed by ir, (1)h nmr, (13)c nmr, hrms techniques or elemental analysis. |
WOS关键词 | ESTROGEN-RECEPTOR ; TAMOXIFEN |
WOS研究方向 | Chemistry |
WOS类目 | Chemistry, Organic |
语种 | 英语 |
WOS记录号 | WOS:000271008100020 |
出版者 | SCIENCE PRESS |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2394656 |
专题 | 中国科学院大学 |
通讯作者 | Zhu Hua |
作者单位 | 1.Chinese Acad Sci, Shanghai Inst Appl Phys, Res Ctr Radiopharmaceut, Shanghai 201800, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
推荐引用方式 GB/T 7714 | Zhu Hua,Huang Liliang,Zhang Chunchun,et al. Synthesis of cyclofenil rhenium tricarbonyl conjugates[J]. Chinese journal of organic chemistry,2009,29(9):1450-1456. |
APA | Zhu Hua,Huang Liliang,Zhang Chunchun,Xu Jia,&Shen Yumei.(2009).Synthesis of cyclofenil rhenium tricarbonyl conjugates.Chinese journal of organic chemistry,29(9),1450-1456. |
MLA | Zhu Hua,et al."Synthesis of cyclofenil rhenium tricarbonyl conjugates".Chinese journal of organic chemistry 29.9(2009):1450-1456. |
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来源:中国科学院大学
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