中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Synthesis of cyclofenil rhenium tricarbonyl conjugates

文献类型:期刊论文

作者Zhu Hua1,2; Huang Liliang1,2; Zhang Chunchun1,2; Xu Jia1; Shen Yumei1
刊名Chinese journal of organic chemistry
出版日期2009-09-01
卷号29期号:9页码:1450-1456
关键词Cyclofenil Rhenium tricarbonyl Breast cancer
ISSN号0253-2786
通讯作者Zhu hua()
英文摘要Starting from 4,4'-dihydroxybenzophenone, three kinds of cyclofenil analogues were prepared by mcmurry coupling. under optimized conditions a series of cyclofenil rhenium(i) tricarbonyl conjugates were prepared as molecular probe precursors of estrogen receptor beta by omega-bromoalkylation and subsequent nucleophilic substitution. the study provides a useful assessment of the stage of the breast cancer by imaging er beta with the spect (single photon emission computed tomography) technique. the structures of final products and the intermediates were confirmed by ir, (1)h nmr, (13)c nmr, hrms techniques or elemental analysis.
WOS关键词ESTROGEN-RECEPTOR ; TAMOXIFEN
WOS研究方向Chemistry
WOS类目Chemistry, Organic
语种英语
WOS记录号WOS:000271008100020
出版者SCIENCE PRESS
URI标识http://www.irgrid.ac.cn/handle/1471x/2394656
专题中国科学院大学
通讯作者Zhu Hua
作者单位1.Chinese Acad Sci, Shanghai Inst Appl Phys, Res Ctr Radiopharmaceut, Shanghai 201800, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Zhu Hua,Huang Liliang,Zhang Chunchun,et al. Synthesis of cyclofenil rhenium tricarbonyl conjugates[J]. Chinese journal of organic chemistry,2009,29(9):1450-1456.
APA Zhu Hua,Huang Liliang,Zhang Chunchun,Xu Jia,&Shen Yumei.(2009).Synthesis of cyclofenil rhenium tricarbonyl conjugates.Chinese journal of organic chemistry,29(9),1450-1456.
MLA Zhu Hua,et al."Synthesis of cyclofenil rhenium tricarbonyl conjugates".Chinese journal of organic chemistry 29.9(2009):1450-1456.

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来源:中国科学院大学

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