Fabrication of size-controlled starch-based nanospheres by nanoprecipitation
文献类型：期刊论文
| 作者 | Tan, Ying1,2; Xu, Kun1; Li, Linglu3; Liu, Chang3; Song, Chunlei1; Wang, Pixin1 |
| 刊名 | Acs applied materials & interfaces
 |
| 出版日期 | 2009-04-01 |
| 卷号 | 1期号:4页码:956-959 |
| 关键词 | Nanospheres Starch acetate Nanoprecipitation Biopolymers Size-controlled Encapsulation |
| ISSN号 | 1944-8244 |
| DOI | 10.1021/am900054f |
| 通讯作者 | Wang, pixin(pxwang@ciac.ji.cn) |
| 英文摘要 | Nanometric and monodisperse starch acetate nanospheres can be prepared through a simple procedure of nanoprecipitation, by the dropwise addition of water to an acetone solution of starch acetate, without any stabilizing agent. this is the first report of the preparation of starch-based nanospheres by this method. the size of the nanospheres obtained can be easily controlled by a number of simple and efficient modifications, i.e., through regulation of the polymer concentration in acetone, the proportions of the water and organic phases, and the molecular weight and degree of substitution of the starch esters. a number of reasons are suggested to explain the observed transitions in the particle size. fluorescence spectroscopic studies proved that these types of nanospheres could be potentially used for the encapsulation of hydrophobic drugs. |
| WOS关键词 | DISPERSION POLYMERIZATION ; DEXTRAN ESTERS ; DRUG-DELIVERY ; PARTICLE-SIZE ; NANOPARTICLES ; NANOCRYSTALS ; WATER ; MICROPARTICLES ; FORMULATION ; RELEASE |
| WOS研究方向 | Science & Technology - Other Topics ; Materials Science |
| WOS类目 | Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000267536100030 |
| 出版者 | AMER CHEMICAL SOC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2396424 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Wang, Pixin |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Changchun Univ Technol, Sch Biol Engn, Changchun 130022, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tan, Ying,Xu, Kun,Li, Linglu,et al. Fabrication of size-controlled starch-based nanospheres by nanoprecipitation[J]. Acs applied materials & interfaces,2009,1(4):956-959. |
| APA | Tan, Ying,Xu, Kun,Li, Linglu,Liu, Chang,Song, Chunlei,&Wang, Pixin.(2009).Fabrication of size-controlled starch-based nanospheres by nanoprecipitation.Acs applied materials & interfaces,1(4),956-959. |
| MLA | Tan, Ying,et al."Fabrication of size-controlled starch-based nanospheres by nanoprecipitation".Acs applied materials & interfaces 1.4(2009):956-959. |
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来源：中国科学院大学
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