Atomic force microscopy study on chlorpromazine-induced morphological changes of living he la cells in vitro
文献类型：期刊论文
| 作者 | Li, Yongjun1,2; Zhang, Jing1,2; Zhang, Bailin1,2 |
| 刊名 | Scanning
 |
| 出版日期 | 2009-11-01 |
| 卷号 | 31期号:6页码:259-265 |
| 关键词 | Atomic force microscopy Human cervical carcinoma cell Cell membrane Living cell Adhesion force |
| ISSN号 | 0161-0457 |
| DOI | 10.1002/sca.20174 |
| 通讯作者 | Zhang, bailin(blzhang@ciac.jl.cn) |
| 英文摘要 | Chlorpromazine (cpz)-induced morphological changes of living human cervical carcinoma cells were investigated by atomic force microscopy in near physiological condition. the results showed that the cell morphology changed visibly with time in the presence of cpz (>21 mu m). the cell membrane shrank gradually and detached finally from the substrate. after being treated with cpz for 50 min. the cell volume increased by about 27.6% while its projective area (cell adhered to the substrate) decreased by about 12%. the mechanism was also discussed. scanning 31: 259-265, 2009. (c) 2010 wiley periodicals, inc. |
| WOS关键词 | SHAPE CHANGES ; MEMBRANE ; ERYTHROCYTES ; AFM |
| WOS研究方向 | Instruments & Instrumentation ; Microscopy |
| WOS类目 | Instruments & Instrumentation ; Microscopy |
| 语种 | 英语 |
| WOS记录号 | WOS:000277680000006 |
| 出版者 | JOHN WILEY & SONS INC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2398307 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zhang, Bailin |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanal Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Yongjun,Zhang, Jing,Zhang, Bailin. Atomic force microscopy study on chlorpromazine-induced morphological changes of living he la cells in vitro[J]. Scanning,2009,31(6):259-265. |
| APA | Li, Yongjun,Zhang, Jing,&Zhang, Bailin.(2009).Atomic force microscopy study on chlorpromazine-induced morphological changes of living he la cells in vitro.Scanning,31(6),259-265. |
| MLA | Li, Yongjun,et al."Atomic force microscopy study on chlorpromazine-induced morphological changes of living he la cells in vitro".Scanning 31.6(2009):259-265. |
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来源：中国科学院大学
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