The role of central ion in chiral recognition by taking phenylalanine as an example
文献类型：期刊论文
| 作者 | Yu Qing; Cao Jie; Lu Gang; Wang ZhiXiang |
| 刊名 | Science in china series b-chemistry
 |
| 出版日期 | 2009-08-01 |
| 卷号 | 52期号:8页码:1136-1141 |
| 关键词 | Chiral crown ether Chiral recognition Diastereoisomer Collision induced dissociation Theoretical calculation |
| ISSN号 | 1006-9291 |
| DOI | 10.1007/s11426-009-0080-5 |
| 通讯作者 | Cao jie(jcao@gucas.ac.cn) |
| 英文摘要 | Chiral recognition of phenylalanine (phe) was achieved in the gas phase by electrospray ionization q-tof tandem mass spectrometry. in this method, two central ions, i.e. proton and divalent copper, were used and chiral crown ether, (+)-2,3,11,12-tetracarboxylic acid-18-crown-6 (18-c-6-tca), was used as a chiral host. dimeric complexes were readily formed by electrospray ionization of a methanol/water (50/50, v/v) solution containing central ions, phe and 18-c-6-tca. the dimeric complex included proton-bound (18-c-6-tca)(phe)h+ and copper-bound deprotonated [cu(2+)(18-c-6-tca)(phe)-h](+) ions were mass selected and then collided with ar in the cid experiments. the chiral recognition capability of these complexes was evaluated using the relative abundance of daughter ion to parent ion. a higher degree of chiral recognition ability was observed with cu(2+) compared to that of h(+). different central ions exhibited distinctive dissociation pathways and unique chiral recognition characteristics. the chiral recognition mechanism was also discussed in detail with the help of the structure of copper-bound complex predicted by theoretical calculation. |
| WOS关键词 | IONIZATION MASS-SPECTROMETRY ; ANTIMONY POTASSIUM TARTRATE ; GAS-PHASE ; KINETIC METHOD ; AMINO-ACIDS ; D,L-AMINO ACIDS ; ION/MOLECULE REACTIONS ; ENANTIOMERIC ANALYSIS ; L-TRYPTOPHAN ; GUEST METHOD |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000268514800010 |
| 出版者 | SCIENCE CHINA PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2398895 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Cao Jie |
| 作者单位 | Chinese Acad Sci, Coll Chem & Chem Engn, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yu Qing,Cao Jie,Lu Gang,et al. The role of central ion in chiral recognition by taking phenylalanine as an example[J]. Science in china series b-chemistry,2009,52(8):1136-1141. |
| APA | Yu Qing,Cao Jie,Lu Gang,&Wang ZhiXiang.(2009).The role of central ion in chiral recognition by taking phenylalanine as an example.Science in china series b-chemistry,52(8),1136-1141. |
| MLA | Yu Qing,et al."The role of central ion in chiral recognition by taking phenylalanine as an example".Science in china series b-chemistry 52.8(2009):1136-1141. |
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来源：中国科学院大学
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