Interaction between xanthoxylin and bovine serum albumin
文献类型：期刊论文
| 作者 | Wen Maogui2; Tian Jianniao2; Huang Yonglin3,4; Bian Hedong1; Chen Zhengfeng2; Liang Hong2 |
| 刊名 | Chinese journal of chemistry
 |
| 出版日期 | 2009-02-01 |
| 卷号 | 27期号:2页码:306-310 |
| 关键词 | Bovine serum albumin Xanthoxylin Fourier transform infrared spectra (ft-ir) Fluorescence quenching |
| ISSN号 | 1001-604X |
| 通讯作者 | Bian hedong(bianhd@mailbox.gxnu.edu.cn) |
| 英文摘要 | The interaction between xanthoxylin (xt) and bovine serum albumin (bsa) under simulative physiological conditions has been analyzed in detail by various spectroscopic techniques including fluorescence, circular dichroism (cd), and fourier transform infrared (ft-ir) spectroscopy. fluorescence quenching data revealed that the quenching constants (k) were 3.31 x 10(5), 2.03 x 10(5) and 0.94 x 10(5) l.mol(-1) at 286, 298 and 310 k, respectively. based on the fluorescence results, the fluorescence quenching mechanism of the interaction between xt and bsa has been found to be combined static and dynamic quenching. thermodynamic parameters delta h(0), delta s(0) and delta g(0) suggested that the hydrophobic force played a main role in binding of xt to bsa. the effect of xt on the conformation of bsa was analyzed by ft-ir spectroscopy and quantitatively calculated from cd spectroscopy with reduction of a-helical content by about 3.9%. in addition, the effect of common ions on the binding constant was also discussed. |
| WOS关键词 | SECONDARY STRUCTURE ; AMIDE-I ; FLUORESCENCE ; SPECTROSCOPY ; PROTEINS ; BINDING ; SPECTRA |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000265281300014 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2400183 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Bian Hedong |
| 作者单位 | 1.Guangxi Normal Univ, Guilin 541004, Guangxi, Peoples R China 2.Guangxi Normal Univ, Minist Educ China, Key Lab Chem & Mol Engn Med Resources, Guilin 54904, Guangxi, Peoples R China 3.Guangxi Inst Bot, Guilin 541004, Guangxi, Peoples R China 4.Chinese Acad Sci, Guilin 541004, Guangxi, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wen Maogui,Tian Jianniao,Huang Yonglin,et al. Interaction between xanthoxylin and bovine serum albumin[J]. Chinese journal of chemistry,2009,27(2):306-310. |
| APA | Wen Maogui,Tian Jianniao,Huang Yonglin,Bian Hedong,Chen Zhengfeng,&Liang Hong.(2009).Interaction between xanthoxylin and bovine serum albumin.Chinese journal of chemistry,27(2),306-310. |
| MLA | Wen Maogui,et al."Interaction between xanthoxylin and bovine serum albumin".Chinese journal of chemistry 27.2(2009):306-310. |
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来源：中国科学院大学
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