Identification of microrna in the protist trichomonas vaginalis
文献类型：期刊论文
| 作者 | Lin, Wei-Chen1,2; Li, Sung-Chou3,4; Lin, Wen-Chang3,5; Shin, Jyh-Wei6; Hu, Song-Nian7; Yu, Xiao-Min7,8; Huang, Ting-Yun9; Chen, Shih-Chieh9; Chen, Hua-Chien10; Chen, Shu-Jen10 |
| 刊名 | Genomics
 |
| 出版日期 | 2009-05-01 |
| 卷号 | 93期号:5页码:487-493 |
| 关键词 | Trichomonas vaginalis Microrna Protist |
| ISSN号 | 0888-7543 |
| DOI | 10.1016/j.ygeno.2009.01.004 |
| 通讯作者 | Tang, petrus(petang@mail.cgu.edu.tw) |
| 英文摘要 | Micrornas (mirnas) are a class of small noncoding rnas that have important regulatory roles in multicellular organisms. however mirna has never been identified experimentally in protist. direct cloning of 438 expressed mirna tags by microrna serial analysis of gene expression from the parasitic protist trichomonas vaginalis identified nine candidate mirnas. bioinformatics analysis of the corresponding genomic region revealed that these mirna candidates contain a classical stern-loop-stern structure of pre-micrornas analysis of the 20 nt long mature tva-mir-001 showed that it is all intergenic mrna located at the scaffold ds113596. tva-mir-001 was differentially expressed in the trophozoite, pseudocyst and amoeboid stages. based oil the experimental results of the present study, we provided solid evidence that protist possesses a mirna regulating network comparable with multicellular organisms for the first time. (c) 2009 elsevier inc. all rights reserved. |
| WOS关键词 | SMALL RNAS ; CAENORHABDITIS-ELEGANS ; ENTAMOEBA-HISTOLYTICA ; TRYPANOSOMA-BRUCEI ; REGULATORY ROLES ; GENOME ; RESOURCE ; COMPLEX ; BIOGENESIS ; PRECURSORS |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Genetics & Heredity |
| WOS类目 | Biotechnology & Applied Microbiology ; Genetics & Heredity |
| 语种 | 英语 |
| WOS记录号 | WOS:000265806100011 |
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2400207 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Tang, Petrus |
| 作者单位 | 1.Chang Gung Univ, Bioinformat Ctr, Mol Regulat & Bioinformat Lab, Tao Yuan 333, Taiwan 2.Chang Gung Univ, Grad Inst Biomed Sci, Div Microbiol, Tao Yuan 333, Taiwan 3.Natl Yang Ming Univ, Inst Biomed Informat, Taipei 112, Taiwan 4.Acad Sinica, Taiwan Int Grad Program Bioinformat, Taipei 115, Taiwan 5.Acad Sinica, Inst Biomed Sci, Taipei 115, Taiwan 6.Natl Cheng Kung Univ, Dept Parasitol, Tainan 70101, Taiwan 7.Chinese Acad Sci, Beijing Inst Genom, Key Lab Genome Sci & Informat, Beijing, Peoples R China 8.Chinese Acad Sci, Grad Univ, Beijing, Peoples R China 9.Chang Gung Univ, Dept Life Sci, Tao Yuan 333, Taiwan 10.Chang Gung Univ, Mol Med Res Ctr, Tao Yuan 333, Taiwan |
| 推荐引用方式 GB/T 7714 | Lin, Wei-Chen,Li, Sung-Chou,Lin, Wen-Chang,et al. Identification of microrna in the protist trichomonas vaginalis[J]. Genomics,2009,93(5):487-493. |
| APA | Lin, Wei-Chen.,Li, Sung-Chou.,Lin, Wen-Chang.,Shin, Jyh-Wei.,Hu, Song-Nian.,...&Tang, Petrus.(2009).Identification of microrna in the protist trichomonas vaginalis.Genomics,93(5),487-493. |
| MLA | Lin, Wei-Chen,et al."Identification of microrna in the protist trichomonas vaginalis".Genomics 93.5(2009):487-493. |
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来源：中国科学院大学
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