Identification of a two-domain antifreeze protein gene in antarctic eelpout lycodichthys dearborni
文献类型：期刊论文
| 作者 | Zhang, Junfang1,2; Deng, Cheng1,2; Wang, Jianshe1; Chen, Liangbiao1 |
| 刊名 | Polar biology
 |
| 出版日期 | 2009 |
| 卷号 | 32期号:1页码:35-40 |
| 关键词 | Type iii antifreeze proteins Antarctic eelpout Gene duplication At-rich region Dna recombination |
| ISSN号 | 0722-4060 |
| DOI | 10.1007/s00300-008-0499-8 |
| 通讯作者 | Chen, liangbiao(lbchen@genetics.ac.cn) |
| 英文摘要 | Type iii antifreeze proteins (afp iii) in the antarctic eelpout lycodichthys dearborni contain at least two size variants-a 7-kda protein family and a specific 14-kda isoform composed of two 7-kda domains linked in tandem. we report the characterization of a two-domain afp iii gene from l. dearborni, and propose that the two-domain afp iii gene arose from a single-domain afp iii gene through duplication and degeneration. at-rich regions played an important role in the degeneration of the duplicated afp iii gene that resulted in the concatenation of two originally separated 7-kda afp-coding exons into a single gene. we also identified a pseudo-afp iii gene interrupted at an at-rich coding region, supporting at-rich regions as hotspots for dna recombination in afp iii gene evolution. interestingly, study of afp iii genes in the related antarctic eelpout pachycara brachycephalum showed absence of two- and multi-domain afp iii genes, indicating that modes of afp iii gene family evolution are specific within species. |
| WOS关键词 | EEL POUT ; PEPTIDE HETEROGENEITY ; TRANSLOCATION ; MECHANISM ; PRECURSOR ; SEQUENCE ; ORIGIN ; FISHES ; TANDEM ; ICE |
| WOS研究方向 | Biodiversity & Conservation ; Environmental Sciences & Ecology |
| WOS类目 | Biodiversity Conservation ; Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:000262536800007 |
| 出版者 | SPRINGER |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2400719 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Chen, Liangbiao |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Mol & Dev Biol, Inst Genet & Dev Biol, Beijing 100101, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Junfang,Deng, Cheng,Wang, Jianshe,et al. Identification of a two-domain antifreeze protein gene in antarctic eelpout lycodichthys dearborni[J]. Polar biology,2009,32(1):35-40. |
| APA | Zhang, Junfang,Deng, Cheng,Wang, Jianshe,&Chen, Liangbiao.(2009).Identification of a two-domain antifreeze protein gene in antarctic eelpout lycodichthys dearborni.Polar biology,32(1),35-40. |
| MLA | Zhang, Junfang,et al."Identification of a two-domain antifreeze protein gene in antarctic eelpout lycodichthys dearborni".Polar biology 32.1(2009):35-40. |
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来源：中国科学院大学
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