中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
In vitro hydrolytic degradation of poly(para-dioxanone) with high molecular weight

文献类型:期刊论文

作者Bai, Wei1,2; Chen, Dongliang1; Li, Qing1; Chen, Hechun1; Zhang, Shenglan1; Huang, Xiaochuan3; Xiong, Cheng-Dong1
刊名Journal of polymer research
出版日期2009-09-01
卷号16期号:5页码:471-480
关键词Poly(para-dioxanone) Degradation Molecular weight Biomaterial Bars
ISSN号1022-9760
DOI10.1007/s10965-008-9250-y
通讯作者Xiong, cheng-dong(xcd1633@yahoo.com.cn)
英文摘要The in vitro hydrolytic degradation of high molecular weight poly (para-dioxanone) was studied by examining the changes of weight retention, water absorption, ph value, tensile strength, break elongation, thermal properties, and morphology of high molecular weight ppdo in phosphate buffered saline (pbs) (ph 7.44) at 37a degrees c for 8 weeks. during the degradation, all samples' weight retention decreased and water absorption increased significantly, whereas hydrolysis rate of ppdo bars varied with molecular weight. compared with lower molecular weight samples, higher molecular weight ppdo samples exhibited higher hydrolysis rate. the samples' glass transition temperature (tg) decreased notably, while the degrees of crystallinity (dc) increased. the samples almost totally lost their tensile strengths and breaking elongation after 4 weeks of degradation. the results suggested that the stability of ppdo in vitro hydrolytic degradation increased with the increase of molecular weight.
WOS关键词POLY-P-DIOXANONE ; POLYGLYCOLIC ACID ; POLY(P-DIOXANONE) ; CRYSTALLIZATION ; POLYDIOXANONE ; MORPHOLOGY ; COPOLYMER ; BEHAVIORS ; SUTURE ; NEAT
WOS研究方向Polymer Science
WOS类目Polymer Science
语种英语
WOS记录号WOS:000268786700002
出版者SPRINGER
URI标识http://www.irgrid.ac.cn/handle/1471x/2401786
专题中国科学院大学
通讯作者Xiong, Cheng-Dong
作者单位1.Chinese Acad Sci, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China
3.Sichuan Univ, Chengdu 610064, Peoples R China
推荐引用方式
GB/T 7714
Bai, Wei,Chen, Dongliang,Li, Qing,et al. In vitro hydrolytic degradation of poly(para-dioxanone) with high molecular weight[J]. Journal of polymer research,2009,16(5):471-480.
APA Bai, Wei.,Chen, Dongliang.,Li, Qing.,Chen, Hechun.,Zhang, Shenglan.,...&Xiong, Cheng-Dong.(2009).In vitro hydrolytic degradation of poly(para-dioxanone) with high molecular weight.Journal of polymer research,16(5),471-480.
MLA Bai, Wei,et al."In vitro hydrolytic degradation of poly(para-dioxanone) with high molecular weight".Journal of polymer research 16.5(2009):471-480.

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来源:中国科学院大学

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