In vitro hydrolytic degradation of poly(para-dioxanone) with high molecular weight
文献类型:期刊论文
作者 | Bai, Wei1,2; Chen, Dongliang1; Li, Qing1; Chen, Hechun1; Zhang, Shenglan1; Huang, Xiaochuan3; Xiong, Cheng-Dong1 |
刊名 | Journal of polymer research
![]() |
出版日期 | 2009-09-01 |
卷号 | 16期号:5页码:471-480 |
关键词 | Poly(para-dioxanone) Degradation Molecular weight Biomaterial Bars |
ISSN号 | 1022-9760 |
DOI | 10.1007/s10965-008-9250-y |
通讯作者 | Xiong, cheng-dong(xcd1633@yahoo.com.cn) |
英文摘要 | The in vitro hydrolytic degradation of high molecular weight poly (para-dioxanone) was studied by examining the changes of weight retention, water absorption, ph value, tensile strength, break elongation, thermal properties, and morphology of high molecular weight ppdo in phosphate buffered saline (pbs) (ph 7.44) at 37a degrees c for 8 weeks. during the degradation, all samples' weight retention decreased and water absorption increased significantly, whereas hydrolysis rate of ppdo bars varied with molecular weight. compared with lower molecular weight samples, higher molecular weight ppdo samples exhibited higher hydrolysis rate. the samples' glass transition temperature (tg) decreased notably, while the degrees of crystallinity (dc) increased. the samples almost totally lost their tensile strengths and breaking elongation after 4 weeks of degradation. the results suggested that the stability of ppdo in vitro hydrolytic degradation increased with the increase of molecular weight. |
WOS关键词 | POLY-P-DIOXANONE ; POLYGLYCOLIC ACID ; POLY(P-DIOXANONE) ; CRYSTALLIZATION ; POLYDIOXANONE ; MORPHOLOGY ; COPOLYMER ; BEHAVIORS ; SUTURE ; NEAT |
WOS研究方向 | Polymer Science |
WOS类目 | Polymer Science |
语种 | 英语 |
WOS记录号 | WOS:000268786700002 |
出版者 | SPRINGER |
URI标识 | http://www.irgrid.ac.cn/handle/1471x/2401786 |
专题 | 中国科学院大学 |
通讯作者 | Xiong, Cheng-Dong |
作者单位 | 1.Chinese Acad Sci, Chengdu Inst Organ Chem, Chengdu 610041, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Sichuan Univ, Chengdu 610064, Peoples R China |
推荐引用方式 GB/T 7714 | Bai, Wei,Chen, Dongliang,Li, Qing,et al. In vitro hydrolytic degradation of poly(para-dioxanone) with high molecular weight[J]. Journal of polymer research,2009,16(5):471-480. |
APA | Bai, Wei.,Chen, Dongliang.,Li, Qing.,Chen, Hechun.,Zhang, Shenglan.,...&Xiong, Cheng-Dong.(2009).In vitro hydrolytic degradation of poly(para-dioxanone) with high molecular weight.Journal of polymer research,16(5),471-480. |
MLA | Bai, Wei,et al."In vitro hydrolytic degradation of poly(para-dioxanone) with high molecular weight".Journal of polymer research 16.5(2009):471-480. |
入库方式: iSwitch采集
来源:中国科学院大学
浏览0
下载0
收藏0
其他版本
除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。