Interaction between f-actin and negatively charged lipids membrane
文献类型：期刊论文
| 作者 | Li Ai-Xue1,2; Cui Xiao-Qiang1; Yang Fan1; Yang Xiu-Rong1 |
| 刊名 | Chinese journal of analytical chemistry
 |
| 出版日期 | 2009 |
| 卷号 | 37期号:1页码:25-29 |
| 关键词 | F-actin Negatively charged lipid membrane Surface plasmon resonance Electrochemical impedance spectroscopy |
| ISSN号 | 0253-3820 |
| 通讯作者 | Li ai-xue() |
| 英文摘要 | Actin is a ubiquitous cytoskeletal protein involved in many fundamental cellular processes. in the cell, actin generally performs its functions in its polymerized form (f-actin). it is well known that the interior membrane of the natural membranes contains a large amount of negatively charged lipids, so the study of the interaction between f-actin and negatively charged lipids would bring some insight oil the interaction between the cytoskeleton and the cell membrane in vivo. the interaction of f-actin and negatively charged lipids membrane has been investigated by surface plasmon resonance and electrochemical impedance spectroscopy. the result shows that f-actin can interact with the negatively charged lipids membrane directly without any intermediate linker protein. ca(2+) can effectively promote this interaction, indicating that in this case the divalent cations played an important role. high concentrations of kcl will inhibit this interaction significantly, indicating that the interaction between f-actin and negatively charged lipid membrane is mainly dominated by electrostatic interactions, although other forces also involved. the results confirm that two mechanisms of the interaction between f-actin and the lipids membrane may exist: direct interaction with lipids and interaction through other membrane protein. |
| WOS关键词 | SURFACE-PLASMON RESONANCE ; DICTYOSTELIUM-DISCOIDEUM ; BILAYER-MEMBRANES |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Analytical |
| 语种 | 英语 |
| WOS记录号 | WOS:000265116600005 |
| 出版者 | ELSEVIER SCIENCE INC |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2404213 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Li Ai-Xue |
| 作者单位 | 1.Chinese Acad Sci, Changchun Inst Appl Chem, State Key Lab Electroanalyt Chem, Changchun 130022, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li Ai-Xue,Cui Xiao-Qiang,Yang Fan,et al. Interaction between f-actin and negatively charged lipids membrane[J]. Chinese journal of analytical chemistry,2009,37(1):25-29. |
| APA | Li Ai-Xue,Cui Xiao-Qiang,Yang Fan,&Yang Xiu-Rong.(2009).Interaction between f-actin and negatively charged lipids membrane.Chinese journal of analytical chemistry,37(1),25-29. |
| MLA | Li Ai-Xue,et al."Interaction between f-actin and negatively charged lipids membrane".Chinese journal of analytical chemistry 37.1(2009):25-29. |
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来源：中国科学院大学
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