Chsminer: a gui tool to identify chromosomal homologous segments
文献类型：期刊论文
| 作者 | Wang, Zhen1,2; Ding, Guohui1,2; Yu, Zhonghao3; Liu, Lei1,4; Li, Yixue1,3,4 |
| 刊名 | Algorithms for molecular biology
 |
| 出版日期 | 2009-01-15 |
| 卷号 | 4页码:7 |
| ISSN号 | 1748-7188 |
| DOI | 10.1186/1748-7188-4-2 |
| 通讯作者 | Liu, lei(leiliu@sibs.ac.cn) |
| 英文摘要 | Background: the identification of chromosomal homologous segments (chs) within and between genomes is essential for comparative genomics. various processes including insertion/deletion and inversion could cause the degeneration of chss. results: here we present a java software chsminer that detects chss based on shared gene content alone. it implements fast greedy search algorithm and rigorous statistical validation, and its friendly graphical interface allows interactive visualization of the results. we tested the software on both simulated and biological realistic data and compared its performance with similar existing software and data source. conclusion: chsminer is characterized by its integrated workflow, fast speed and convenient usage. it will be useful for both experimentalists and bioinformaticians interested in the structure and evolution of genomes. |
| WOS关键词 | STATISTICAL DETECTION ; COMPARATIVE GENOMICS ; EVOLUTION ; DUPLICATIONS ; FAMILIES |
| WOS研究方向 | Biochemistry & Molecular Biology ; Biotechnology & Applied Microbiology ; Mathematical & Computational Biology |
| WOS类目 | Biochemical Research Methods ; Biotechnology & Applied Microbiology ; Mathematical & Computational Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000263952300001 |
| 出版者 | BIOMED CENTRAL LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2404907 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Liu, Lei |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Biol Sci, Key Lab Syst Biol, Shanghai 200031, Peoples R China 2.Chinese Acad Sci, Grad Sch, Shanghai 200031, Peoples R China 3.Shanghai Jiao Tong Univ, Coll Life Sci & Biotechnol, Shanghai 200240, Peoples R China 4.Shanghai Ctr Bioinformat Technol, Shanghai 200235, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Zhen,Ding, Guohui,Yu, Zhonghao,et al. Chsminer: a gui tool to identify chromosomal homologous segments[J]. Algorithms for molecular biology,2009,4:7. |
| APA | Wang, Zhen,Ding, Guohui,Yu, Zhonghao,Liu, Lei,&Li, Yixue.(2009).Chsminer: a gui tool to identify chromosomal homologous segments.Algorithms for molecular biology,4,7. |
| MLA | Wang, Zhen,et al."Chsminer: a gui tool to identify chromosomal homologous segments".Algorithms for molecular biology 4(2009):7. |
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来源：中国科学院大学
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