Bipolar linear algebra and yinyang-n-element cellular networks for equilibrium-based biosystem simulation and regulation
文献类型：期刊论文
| 作者 | Zhang, Wen-Ran1; Zhang, Jane H.2; Shi, Yong3,4; Chen, Su-Shing5 |
| 刊名 | Journal of biological systems
 |
| 出版日期 | 2009-12-01 |
| 卷号 | 17期号:4页码:547-576 |
| 关键词 | Repression and activation Bipolar linear algebra Yinyang-n-element bipolar cellular networks Equilibrium and non-equilibrium conditions Aging and degeneration Simulation and regulation |
| ISSN号 | 0218-3390 |
| DOI | 10.1142/s0218339009002958 |
| 通讯作者 | Zhang, wen-ran(wrzhang@georgiasouthern.edu) |
| 英文摘要 | Bipolar linear algebra (bla) and yinyang-n-element bipolar cellular networks (bcns) are presented for equilibrium-based biological simulation and regulation at the system, molecular, and genetic levels. bipolar fusion, interaction, oscillation, and quantum entanglement with growing, aging, degenerating, equilibrium, and non-equilibrium properties are mathematically characterized; bipolar dynamic equations with metabolic nourishing and regulating relations are formulated; global and local equilibrium conditions are established and proved. two families of yinyang-n-element bcns are compared and analyzed: one family has predefined nourishing and regulation cycles following the classical yinyang-5-element protocol in traditional chinese medicine (tcm); another family has random connectivity and link weights. applicability of the theory is illustrated in equilibrium and non-equilibrium simulation of bio-agent interaction and regulation. the significance of this work is two-fold: (1) bla provides a unique and unifying mathematical foundation for bipolar fusion, interaction, and oscillation in biophysics and bioeconomics; (2) yinyang-n-element bcns provide a unique and unifying architecture for modeling equilibrium and non-equilibrium processes at the system, molecular, and genetic levels. |
| WOS关键词 | YIN YANG-1 YY1 ; DECISION ; MODEL ; TRANSCRIPTION ; REPRESSION ; YIN-YANG-1 ; PROTEIN ; SYSTEM ; SETS |
| WOS研究方向 | Life Sciences & Biomedicine - Other Topics ; Mathematical & Computational Biology |
| WOS类目 | Biology ; Mathematical & Computational Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000273426400002 |
| 出版者 | WORLD SCIENTIFIC PUBL CO PTE LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2404967 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zhang, Wen-Ran |
| 作者单位 | 1.Georgia So Univ, Dept Comp Sci, Statesboro, GA 30460 USA 2.Georgia So Univ, Dept Math Sci, Statesboro, GA 30460 USA 3.Chinese Acad Sci, Res Ctr Fictitious Econ & Data Sci, Beijing 100080, Peoples R China 4.Univ Nebraska, Coll Informat Sci & Technol, Omaha, NE 68118 USA 5.Chinese Acad Sci, Shanghai Inst Biol Sci, CAS MPG Partner Inst Computat Biol, Shanghai 200031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Wen-Ran,Zhang, Jane H.,Shi, Yong,et al. Bipolar linear algebra and yinyang-n-element cellular networks for equilibrium-based biosystem simulation and regulation[J]. Journal of biological systems,2009,17(4):547-576. |
| APA | Zhang, Wen-Ran,Zhang, Jane H.,Shi, Yong,&Chen, Su-Shing.(2009).Bipolar linear algebra and yinyang-n-element cellular networks for equilibrium-based biosystem simulation and regulation.Journal of biological systems,17(4),547-576. |
| MLA | Zhang, Wen-Ran,et al."Bipolar linear algebra and yinyang-n-element cellular networks for equilibrium-based biosystem simulation and regulation".Journal of biological systems 17.4(2009):547-576. |
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来源：中国科学院大学
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