Evidence of a major role of gp64 in group i alphabaculovirus evolution
文献类型：期刊论文
| 作者 | Jiang, Yue1,2,3; Deng, Fei1,2; Rayner, Simon1,2; Wang, Hualin1,2; Hu, Zhihong1,2 |
| 刊名 | Virus research
 |
| 出版日期 | 2009-06-01 |
| 卷号 | 142期号:1-2页码:85-91 |
| 关键词 | Lepidopteran baculovirus Evolution rate Ka/ks ratio Selection pressure Gp64 F protein |
| ISSN号 | 0168-1702 |
| DOI | 10.1016/j.virusres.2009.01.015 |
| 通讯作者 | Hu, zhihong(huzh@wh.iov.cn) |
| 英文摘要 | Previous investigations suggest that the divergence of the group i alphabaculoviruses was later than that of the group 11 alphabaculoviruses, however, there is no quantitative data to support this hypothesis. to examine this theory, the evolutionary rates of the 30 core genes that are conserved among all baculoviruses and the 11 unique genes among group i alphabaculoviruses were estimated in this report. for core genes, the synonymous and nonsynonymous substitution rates (ks and ka) were found to be significantly different among different groups, with the rates being granulovirus > group ii > group i. among the 11 unique genes, gp64 was found to have the highest amino acid identity and the lowest omega (ka/ks) and ka values. the significant difference in the selection pressure was found in the f-like protein. these analyses suggests the following interpretation: (i) group i evolved from an ancestral group 11 alphabaculovirus that had 11 genes not present in other members of this group; (ii) the acquisition of the gp64 gene may have stimulated or initiated the formation of the group i as a major lineage distinct from group ii; and (iii) after being functionally displaced by gp64, the f-like gene of group i evolved under a relaxed selection pressure that lead to the partial lost of its function. (c) 2009 elsevier b.v. all rights reserved. |
| WOS关键词 | ENVELOPE FUSION PROTEIN ; CALIFORNICA MULTICAPSID NUCLEOPOLYHEDROVIRUS ; PHYLOGENETIC ANALYSIS ; SUBSTITUTION RATES ; BUDDED VIRUS ; GENOME SEQUENCE ; BACULOVIRUS ; GENE ; IDENTIFICATION ; COEVOLUTION |
| WOS研究方向 | Virology |
| WOS类目 | Virology |
| 语种 | 英语 |
| WOS记录号 | WOS:000266366600011 |
| 出版者 | ELSEVIER SCIENCE BV |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2405374 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Hu, Zhihong |
| 作者单位 | 1.Chinese Acad Sci, State Key Lab Virol, Wuhan Inst Virol, Wuhan 430071, Peoples R China 2.Chinese Acad Sci, Joint Lab Invertebrate Virol, Wuhan Inst Virol, Wuhan 430071, Peoples R China 3.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Yue,Deng, Fei,Rayner, Simon,et al. Evidence of a major role of gp64 in group i alphabaculovirus evolution[J]. Virus research,2009,142(1-2):85-91. |
| APA | Jiang, Yue,Deng, Fei,Rayner, Simon,Wang, Hualin,&Hu, Zhihong.(2009).Evidence of a major role of gp64 in group i alphabaculovirus evolution.Virus research,142(1-2),85-91. |
| MLA | Jiang, Yue,et al."Evidence of a major role of gp64 in group i alphabaculovirus evolution".Virus research 142.1-2(2009):85-91. |
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来源：中国科学院大学
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