Surfactant-assisted sonochemical synthesis of hollow calcium silicate hydrate (csh) microspheres for drug delivery
文献类型：期刊论文
| 作者 | Zhang, Meili1,2; Chang, Jiang1 |
| 刊名 | Ultrasonics sonochemistry
 |
| 出版日期 | 2010-06-01 |
| 卷号 | 17期号:5页码:789-792 |
| 关键词 | Calcium silicate hydrate Hollow spheres Ultrasound radiation Template Controlled release |
| ISSN号 | 1350-4177 |
| DOI | 10.1016/j.ultsonch.2010.01.012 |
| 通讯作者 | Chang, jiang(jchang@mail.sic.ac.cn) |
| 英文摘要 | Hollow calcium silicate hydrate (csh) microspheres with diameters around 1 mu m were synthesized by a surfactant-assisted sonochemical route, and the products were characterized by xrd, sem, fetem and bet techniques. the results suggested that the ultrasound radiation, surfactant and ca source were important factors which affected the formation of hollow microspheres. based on the observation of products in different reaction systems, the possible mechanism for the formation of hollow csh spheres was discussed. furthermore, gentamicin, a typical anti-inflammatory drug, was used to investigate the drug loading and release behavior of the hollow spheres. the results indicated that csh hollow spheres had high drug loading capacity and favorable drug release behavior, and might be used for preparation of bone grafts with drug delivery properties. (c) 2010 elsevier b.v. all rights reserved. |
| WOS关键词 | SIMULATED BODY-FLUID ; IN-VITRO ; CERAMICS ; HYDROXYAPATITE ; NANOSPHERES ; MORPHOLOGY |
| WOS研究方向 | Acoustics ; Chemistry |
| WOS类目 | Acoustics ; Chemistry, Multidisciplinary |
| 语种 | 英语 |
| WOS记录号 | WOS:000278297400011 |
| 出版者 | ELSEVIER SCIENCE BV |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2406574 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Chang, Jiang |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Ceram, State Key Lab High Performance Ceram & Superfine, Shanghai 200050, Peoples R China 2.Chinese Acad Sci, Grad Sch, Shanghai 200050, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Meili,Chang, Jiang. Surfactant-assisted sonochemical synthesis of hollow calcium silicate hydrate (csh) microspheres for drug delivery[J]. Ultrasonics sonochemistry,2010,17(5):789-792. |
| APA | Zhang, Meili,&Chang, Jiang.(2010).Surfactant-assisted sonochemical synthesis of hollow calcium silicate hydrate (csh) microspheres for drug delivery.Ultrasonics sonochemistry,17(5),789-792. |
| MLA | Zhang, Meili,et al."Surfactant-assisted sonochemical synthesis of hollow calcium silicate hydrate (csh) microspheres for drug delivery".Ultrasonics sonochemistry 17.5(2010):789-792. |
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来源：中国科学院大学
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