Chiral primary amine thiourea promoted highly enantioselective michael reactions of isobutylaldehyde with maleimides
文献类型：期刊论文
| 作者 | Bai, Jian-Fei1,2; Peng, Lin1,2; Wang, Liang-liang1,2; Wang, Li-Xin1; Xu, Xiao-Ying1 |
| 刊名 | Tetrahedron
 |
| 出版日期 | 2010-11-13 |
| 卷号 | 66期号:46页码:8928-8932 |
| 关键词 | Primary amine thiourea Michael reactions Isobutylaldehyde Maleimides Enantioselective |
| ISSN号 | 0040-4020 |
| DOI | 10.1016/j.tet2010.09.044 |
| 通讯作者 | Wang, li-xin(wlxioc@cioc.ac.cn) |
| 英文摘要 | Chiral primary amine thiourea catalysts were first successfully applied to promote michael addition of isobutyraldehyde to maleimides. a variety of n-aryl and n-aliphatic maleimides provided michael adducts in excellent yields (up to 98%) and enantioselectivities (up to 99% ee) with 5 mol % catalyst. (c) 2010 elsevier ltd. all rights reserved. |
| WOS关键词 | HYDROGEN-BONDING DONORS ; CATALYZED ASYMMETRIC 1,4-ADDITION ; DIRECT CONJUGATE ADDITION ; BIFUNCTIONAL THIOUREA ; ALPHA,ALPHA-DISUBSTITUTED ALDEHYDES ; 1,3-DICARBONYL COMPOUNDS ; ALPHA,BETA-UNSATURATED KETONES ; EFFICIENT ORGANOCATALYSTS ; QUATERNARY STEREOCENTERS ; SUBSTITUTED MALEIMIDES |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000284499100018 |
| 出版者 | PERGAMON-ELSEVIER SCIENCE LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2407005 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Wang, Li-Xin |
| 作者单位 | 1.Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmetr Synth & Chirotechnol Sichuan Pro, Chengdu 610041, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Bai, Jian-Fei,Peng, Lin,Wang, Liang-liang,et al. Chiral primary amine thiourea promoted highly enantioselective michael reactions of isobutylaldehyde with maleimides[J]. Tetrahedron,2010,66(46):8928-8932. |
| APA | Bai, Jian-Fei,Peng, Lin,Wang, Liang-liang,Wang, Li-Xin,&Xu, Xiao-Ying.(2010).Chiral primary amine thiourea promoted highly enantioselective michael reactions of isobutylaldehyde with maleimides.Tetrahedron,66(46),8928-8932. |
| MLA | Bai, Jian-Fei,et al."Chiral primary amine thiourea promoted highly enantioselective michael reactions of isobutylaldehyde with maleimides".Tetrahedron 66.46(2010):8928-8932. |
入库方式： iSwitch采集
来源：中国科学院大学
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。