Exploratory studies en route to 5-alkyl-hyacinthacines: synthesis of 5-epi-(-)-hyacinthacine a(3) and (-)-hyacinthacine a(3)
文献类型：期刊论文
| 作者 | Hu, Xiang-Guo1,2; Jia, Yue-Mei1; Xiang, Junfeng1; Yu, Chu-Yi1 |
| 刊名 | Synlett
 |
| 出版日期 | 2010-04-01 |
| 期号 | 6页码:982-986 |
| 关键词 | Nitrone Alpha-amino nitrile Iminosugars Polyhydroxylated pyrrolizidine Hyacinthacine |
| ISSN号 | 0936-5214 |
| DOI | 10.1055/s-0029-1219540 |
| 通讯作者 | Yu, chu-yi(yucy@iccas.ac.cn) |
| 英文摘要 | Synthesis of 5-epi-(-)-hyacinthacine a(3) and (-)-hyacinthacine a(3) has been achieved from the d-xylose-derived polyhydroxylated cyclic nitrone. our synthetic strategy is potentially general and flexible for the synthesis of both epimers of 5-alkyl-hyacinthacines. |
| WOS关键词 | LYSOSOMAL STORAGE DISORDERS ; 1ST TOTAL SYNTHESIS ; CYCLIC NITRONES ; GLYCOSIDASE INHIBITORS ; PYRROLIZIDINE ALKALOIDS ; ASYMMETRIC-SYNTHESIS ; ENANTIOSPECIFIC SYNTHESIS ; NUCLEOPHILIC ADDITIONS ; ENANTIOSELECTIVE SYNTHESIS ; 5-EPI-HYACINTHACINE A(3) |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000275848800032 |
| 出版者 | GEORG THIEME VERLAG KG |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2407118 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Yu, Chu-Yi |
| 作者单位 | 1.Chinese Acad Sci, Inst Chem, BNLMS, Key Lab Mol Recognit & Funct, Beijing 100190, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Xiang-Guo,Jia, Yue-Mei,Xiang, Junfeng,et al. Exploratory studies en route to 5-alkyl-hyacinthacines: synthesis of 5-epi-(-)-hyacinthacine a(3) and (-)-hyacinthacine a(3)[J]. Synlett,2010(6):982-986. |
| APA | Hu, Xiang-Guo,Jia, Yue-Mei,Xiang, Junfeng,&Yu, Chu-Yi.(2010).Exploratory studies en route to 5-alkyl-hyacinthacines: synthesis of 5-epi-(-)-hyacinthacine a(3) and (-)-hyacinthacine a(3).Synlett(6),982-986. |
| MLA | Hu, Xiang-Guo,et al."Exploratory studies en route to 5-alkyl-hyacinthacines: synthesis of 5-epi-(-)-hyacinthacine a(3) and (-)-hyacinthacine a(3)".Synlett .6(2010):982-986. |
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来源：中国科学院大学
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