Asymmetric michael addition of aromatic ketones to nitroolefins catalyzed by simple chiral bifunctional primary amine-thioureas
文献类型：期刊论文
| 作者 | Wang, Liangliang1,2; Xu, Xiaoying1; Huang, Jun1,2; Peng, Lin1,2; Huang, Qingchun1; Wang, Lixin1 |
| 刊名 | Letters in organic chemistry
 |
| 出版日期 | 2010-07-01 |
| 卷号 | 7期号:5页码:367-372 |
| 关键词 | Organocatalyst Michael addition Aromatic ketones Nitroolefins Primary-amine thiourea |
| ISSN号 | 1570-1786 |
| 通讯作者 | Wang, lixin(wlxioc@cioc.ac.cn) |
| 英文摘要 | Simple chiral primary amine-thiourea catalysts derived from chiral 1,2-diphenylethylenediamine were found to catalyze direct michael addition of aromatic ketones to nitroolefins with good enantioselectives (up to 86% ee) and excellent yields (up to 97%) for a broad range of substrates and successfully used in the preparation of (r)-balcofen. |
| WOS关键词 | HYDROGEN-BONDING DONORS ; DIRECT CONJUGATE ADDITION ; NITRO-MANNICH REACTIONS ; AZA-HENRY REACTION ; ENANTIOSELECTIVE MICHAEL ; PYRROLIDINE-THIOUREA ; ENAMINE CATALYSIS ; ORGANOCATALYSTS ; WATER ; NITROALKENES |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000277886900004 |
| 出版者 | BENTHAM SCIENCE PUBL LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2407933 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Wang, Lixin |
| 作者单位 | 1.Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmetr Synth & Chirotechnol Sichuan Pro, Chengdu 610041, Sichuan Prov, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing 10039, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Liangliang,Xu, Xiaoying,Huang, Jun,et al. Asymmetric michael addition of aromatic ketones to nitroolefins catalyzed by simple chiral bifunctional primary amine-thioureas[J]. Letters in organic chemistry,2010,7(5):367-372. |
| APA | Wang, Liangliang,Xu, Xiaoying,Huang, Jun,Peng, Lin,Huang, Qingchun,&Wang, Lixin.(2010).Asymmetric michael addition of aromatic ketones to nitroolefins catalyzed by simple chiral bifunctional primary amine-thioureas.Letters in organic chemistry,7(5),367-372. |
| MLA | Wang, Liangliang,et al."Asymmetric michael addition of aromatic ketones to nitroolefins catalyzed by simple chiral bifunctional primary amine-thioureas".Letters in organic chemistry 7.5(2010):367-372. |
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来源：中国科学院大学
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