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Chinese Academy of Sciences Institutional Repositories Grid
Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from laminaria japonica

文献类型:期刊论文

作者Wang, Jing1,2; Zhang, Quanbin1; Zhang, Zhongshan1,2; Song, Houfang1,2; Li, Pengcheng1
刊名International journal of biological macromolecules
出版日期2010
卷号46期号:1页码:6-12
关键词Low molecular weight fucoidan Laminaria japonica Antioxidant Anticoagulant
ISSN号0141-8130
DOI10.1016/j.ijbiomac.2009.10.015
通讯作者Zhang, quanbin(qbzhang@ms.qdio.ac.cn)
英文摘要A low molecular weight fucoidan (dfps), obtained from the brown seaweed laminaria japonica, was separated into three fractions by anion-exchange column chromatography. all three fractions (df1, df2, df3) predominantly contained variety fucose, galactose and sulfate group. the antioxidant and anticoagulant activities of these fractions were investigated. the results showed that all fractions possessed considerable antioxidant activities, df1 was most active. all samples inhibited coagulant in aptt, tt and pt assays obviously. available data presented the content of sulfate group, the molar ratio of sulfate/fucose and sulfate/total sugar, and the molecular weight played an important role on antioxidant and anticoagulant activity. (c) 2009 elsevier b.v. all rights reserved.
WOS关键词RADICAL SCAVENGING ACTIVITY ; OXIDATIVE STRESS ; CHROMATOGRAPHY ; HEPARIN ; OXYGEN ; TEA ; ROS ; XA
WOS研究方向Biochemistry & Molecular Biology
WOS类目Biochemistry & Molecular Biology
语种英语
WOS记录号WOS:000274971900002
出版者ELSEVIER SCIENCE BV
URI标识http://www.irgrid.ac.cn/handle/1471x/2409415
专题中国科学院大学
通讯作者Zhang, Quanbin
作者单位1.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China
2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714
Wang, Jing,Zhang, Quanbin,Zhang, Zhongshan,et al. Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from laminaria japonica[J]. International journal of biological macromolecules,2010,46(1):6-12.
APA Wang, Jing,Zhang, Quanbin,Zhang, Zhongshan,Song, Houfang,&Li, Pengcheng.(2010).Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from laminaria japonica.International journal of biological macromolecules,46(1),6-12.
MLA Wang, Jing,et al."Potential antioxidant and anticoagulant capacity of low molecular weight fucoidan fractions extracted from laminaria japonica".International journal of biological macromolecules 46.1(2010):6-12.

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来源:中国科学院大学

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