Mapping informative clusters in a hierarchial framework of fmri multivariate analysis
文献类型：期刊论文
| 作者 | Xu, Rui1; Zhen, Zonglei2; Liu, Jia1,2 |
| 刊名 | Plos one
 |
| 出版日期 | 2010-11-30 |
| 卷号 | 5期号:11页码:8 |
| ISSN号 | 1932-6203 |
| DOI | 10.1371/journal.pone.0015065 |
| 通讯作者 | Xu, rui() |
| 英文摘要 | Pattern recognition methods have become increasingly popular in fmri data analysis, which are powerful in discriminating between multi-voxel patterns of brain activities associated with different mental states. however, when they are used in functional brain mapping, the location of discriminative voxels varies significantly, raising difficulties in interpreting the locus of the effect. here we proposed a hierarchical framework of multivariate approach that maps informative clusters rather than voxels to achieve reliable functional brain mapping without compromising the discriminative power. in particular, we first searched for local homogeneous clusters that consisted of voxels with similar response profiles. then, a multi-voxel classifier was built for each cluster to extract discriminative information from the multi-voxel patterns. finally, through multivariate ranking, outputs from the classifiers were served as a multi-cluster pattern to identify informative clusters by examining interactions among clusters. results from both simulated and real fmri data demonstrated that this hierarchical approach showed better performance in the robustness of functional brain mapping than traditional voxel-based multivariate methods. in addition, the mapped clusters were highly overlapped for two perceptually equivalent object categories, further confirming the validity of our approach. in short, the hierarchical framework of multivariate approach is suitable for both pattern classification and brain mapping in fmri studies. |
| WOS关键词 | SUPPORT VECTOR MACHINES ; SURFACE-BASED ANALYSIS ; HUMAN VISUAL-CORTEX ; TEMPORAL CORTEX ; FUNCTIONAL MRI ; BRAIN ; PATTERNS ; SELECTION ; FACES ; CLASSIFICATION |
| WOS研究方向 | Science & Technology - Other Topics |
| WOS类目 | Multidisciplinary Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000284755100057 |
| 出版者 | PUBLIC LIBRARY SCIENCE |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2409629 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Xu, Rui |
| 作者单位 | 1.Chinese Acad Sci, Grad Univ, Coll Life Sci, Beijing, Peoples R China 2.Beijing Normal Univ, State Key Lab Cognit Neurosci & Learning, Beijing 100875, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Rui,Zhen, Zonglei,Liu, Jia. Mapping informative clusters in a hierarchial framework of fmri multivariate analysis[J]. Plos one,2010,5(11):8. |
| APA | Xu, Rui,Zhen, Zonglei,&Liu, Jia.(2010).Mapping informative clusters in a hierarchial framework of fmri multivariate analysis.Plos one,5(11),8. |
| MLA | Xu, Rui,et al."Mapping informative clusters in a hierarchial framework of fmri multivariate analysis".Plos one 5.11(2010):8. |
入库方式： iSwitch采集
来源：中国科学院大学
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。