Acute and chronic un-ionized ammonia toxicity to 'all-fish' growth hormone transgenic common carp (cyprinus carpio l.)
文献类型：期刊论文
| 作者 | Guan Bo1,2; Hu Wei1; Zhang TangLin1; Duan Ming1,2; Li DeLiang1,2; Wang YaPing1; Zhu ZuoYan1 |
| 刊名 | Chinese science bulletin
 |
| 出版日期 | 2010-12-01 |
| 卷号 | 55期号:35页码:4032-4036 |
| 关键词 | Transgenic common carp Growth hormone Un-ionized ammonia Toxicity Mortality |
| ISSN号 | 1001-6538 |
| DOI | 10.1007/s11434-010-4165-5 |
| 通讯作者 | Hu wei(huwei@ihb.ac.cn) |
| 英文摘要 | Ammonia is toxic to fish in natural and artificial waters. we evaluated the acute (96 h) and chronic (21 d) toxicity of un-ionized ammonia to gh transgenic common carp (cyprinus carpio l.) and non-transgenic common carp using a static-renewal bioassay. the 24, 48, 72 and 96 h median lethal concentrations (lc(50)) of un-ionized ammonia were slightly lower in transgenic carp (2.64, 2.44, 2.28 and 2.16 mg n/l, respectively) than in non-transgenic carp (2.70, 2.64, 2.52 and 2.33 mg n/l, respectively). similarly, the median lethal time (lt(50)) was significantly shorter for transgenic carp (1.41, 7.91 and 117.42 h) than for non-transgenic common carp (2.53, 14.06 and 150.44 h) following exposure to 3.86, 3.29, or 2.09 mg n/l, respectively. moreover, the mortality of transgenic carp was significantly higher than that of non-transgenic carp at all un-ionized ammonia concentrations ((0.91 +/- 0.12), (0.48 +/- 0.06) and (0.12 +/- 0.01) mg n/l) during the 21 d chronic toxicity test. our results suggest that gh transgenic carp are less tolerant of un-ionized ammonia than non-transgenic carp. our data are useful for evaluating potential environmental risk, optimizing stocking density in intensive aquaculture and establishing water quality criteria for ammonia in aquaculture. |
| WOS关键词 | TILAPIA OREOCHROMIS-NILOTICUS ; ONCORHYNCHUS-MYKISS ; RAINBOW-TROUT ; RECEPTOR ; EXPOSURE ; RAT ; SUSCEPTIBILITY ; TRANSCRIPTS ; PERFORMANCE ; EXPRESSION |
| WOS研究方向 | Science & Technology - Other Topics |
| WOS类目 | Multidisciplinary Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000285196000009 |
| 出版者 | SCIENCE CHINA PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2412106 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Hu Wei |
| 作者单位 | 1.Chinese Acad Sci, Inst Hydrobiol, State Key Lab Freshwater Ecol & Biotechnol, Wuhan 430072, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Guan Bo,Hu Wei,Zhang TangLin,et al. Acute and chronic un-ionized ammonia toxicity to 'all-fish' growth hormone transgenic common carp (cyprinus carpio l.)[J]. Chinese science bulletin,2010,55(35):4032-4036. |
| APA | Guan Bo.,Hu Wei.,Zhang TangLin.,Duan Ming.,Li DeLiang.,...&Zhu ZuoYan.(2010).Acute and chronic un-ionized ammonia toxicity to 'all-fish' growth hormone transgenic common carp (cyprinus carpio l.).Chinese science bulletin,55(35),4032-4036. |
| MLA | Guan Bo,et al."Acute and chronic un-ionized ammonia toxicity to 'all-fish' growth hormone transgenic common carp (cyprinus carpio l.)".Chinese science bulletin 55.35(2010):4032-4036. |
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来源：中国科学院大学
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