Molecular cloning, segmental distribution and ontogenetic expression of the amino acid transporter y(+)lat1 in intestine of the tibetan suckling piglets
文献类型：期刊论文
| 作者 | Gu, Wanting2; Fang, Jun1; Wang, Wence2; Fan, Ming3; Geng, Meimei2; Li, Teijun2; Chu, Wuyin4 |
| 刊名 | Journal of food agriculture & environment
 |
| 出版日期 | 2010-04-01 |
| 卷号 | 8期号:2页码:1067-1072 |
| 关键词 | Amino acid transporter Y(+)lat1 Tibetan suckling piglets Ontogenetic expression |
| ISSN号 | 1459-0255 |
| 通讯作者 | Fang, jun(fangjun1973@yahoo.com.cn) |
| 英文摘要 | The y(+)lat1 gene is a member of solute carrier family that encodes a protein, which plays a significant function in transport of neutral and dibasic amino acids. the tibetan pig is an excellent local variety in china, which is able to tolerate and survive under the adverse conditions. the study cloned the cdna sequence of tibetan pig y(+)lat1 (genbank accession #eu390782), and evaluated the tissue distribution and developmental expression of y(+)lat1 mrna and protein in different parts of intestine in tibetan suckling piglets. the results show that the y(+)lat1 cdna encodes 511 deduced amino acid residues and 12 putative transmembrane domains, which can be widely detected in many organs in tibetan piglets. expression patterns were similar in jejunum and ileum, where the mrna and protein level was decreased before the suckling period and increased until day 35, duodenum changed reversely. the jejunum posterior is the predominant expressional tissue in all days. these results indicated that the ontogenesis expression of y(+)lat1 was not only differentially regulated by early development age but also differentially with distributed tissues along the small intestine. |
| WOS关键词 | LYSINURIC PROTEIN INTOLERANCE ; EARLY-WEANED PIGLETS ; DIETARY SUPPLEMENTATION ; GROWTH-PERFORMANCE ; SKELETAL-MUSCLE ; NEONATAL PIGS ; IDENTIFICATION ; SLC7A7 ; FAMILY ; GENE |
| WOS研究方向 | Food Science & Technology |
| WOS类目 | Food Science & Technology |
| 语种 | 英语 |
| WOS记录号 | WOS:000279103700085 |
| 出版者 | WFL PUBL |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2414879 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Fang, Jun |
| 作者单位 | 1.Hunan Agr Univ, Coll Biosci & Biotechnol, Changsha 410125, Hunan, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100039, Peoples R China 3.Univ Guelph, Dept Anim & Poultry Sci, Guelph, ON N1G 2W1, Canada 4.Changsha Univ, Dept Bioengn & Environm Sci, Changsha 410003, Hunan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Gu, Wanting,Fang, Jun,Wang, Wence,et al. Molecular cloning, segmental distribution and ontogenetic expression of the amino acid transporter y(+)lat1 in intestine of the tibetan suckling piglets[J]. Journal of food agriculture & environment,2010,8(2):1067-1072. |
| APA | Gu, Wanting.,Fang, Jun.,Wang, Wence.,Fan, Ming.,Geng, Meimei.,...&Chu, Wuyin.(2010).Molecular cloning, segmental distribution and ontogenetic expression of the amino acid transporter y(+)lat1 in intestine of the tibetan suckling piglets.Journal of food agriculture & environment,8(2),1067-1072. |
| MLA | Gu, Wanting,et al."Molecular cloning, segmental distribution and ontogenetic expression of the amino acid transporter y(+)lat1 in intestine of the tibetan suckling piglets".Journal of food agriculture & environment 8.2(2010):1067-1072. |
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来源：中国科学院大学
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