The first highly enantioselective lewis base organocatalyzed hydrosilylation of alpha-imino esters
文献类型：期刊论文
| 作者 | Xue, Zhou-Yang1,2; Jiang, Yan1,2; Yuan, Wei-Cheng1; Zhang, Xiao-Mei1 |
| 刊名 | European journal of organic chemistry
 |
| 出版日期 | 2010-02-01 |
| 期号 | 4页码:616-619 |
| 关键词 | Amino acids Enantioselectivity Hydrosilylation Lewis bases Organocatalysis |
| ISSN号 | 1434-193X |
| DOI | 10.1002/ejoc.200901312 |
| 通讯作者 | Zhang, xiao-mei(xmzhang@cioc.ac.cn) |
| 英文摘要 | Novel, chiral lewis base organocatalysts, which displayed poor enantioselection in the hydrosilylation of n-aryl beta-enamino esters, were found to be the catalysts of choice in the hydrosilylation of alpha-imino esters. in the presence of 10 mol-% of the best catalyst, various alpha-imino esters underwent enantioselective hydrosilylation to provide a wide range of chiral alpha-amino esters with good yields (up to 97%) and high enantioselectivities (up to 93% ee) except for some special substrates. |
| WOS关键词 | PHASE-TRANSFER CATALYSIS ; AMINO-ACIDS ; ASYMMETRIC HYDROGENATION ; PHOSPHORIC-ACID ; BRONSTED ACID ; REDUCTION ; TRICHLOROSILANE ; KETIMINES |
| WOS研究方向 | Chemistry |
| WOS类目 | Chemistry, Organic |
| 语种 | 英语 |
| WOS记录号 | WOS:000274449000004 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2415315 |
| 专题 | 中国科学院大学 |
| 通讯作者 | Zhang, Xiao-Mei |
| 作者单位 | 1.Chinese Acad Sci, Chengdu Inst Organ Chem, Key Lab Asymmetr Synth & Chiral Technol Sichuan P, Chengdu 610041, Peoples R China 2.Chinese Acad Sci, Grad Sch, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xue, Zhou-Yang,Jiang, Yan,Yuan, Wei-Cheng,et al. The first highly enantioselective lewis base organocatalyzed hydrosilylation of alpha-imino esters[J]. European journal of organic chemistry,2010(4):616-619. |
| APA | Xue, Zhou-Yang,Jiang, Yan,Yuan, Wei-Cheng,&Zhang, Xiao-Mei.(2010).The first highly enantioselective lewis base organocatalyzed hydrosilylation of alpha-imino esters.European journal of organic chemistry(4),616-619. |
| MLA | Xue, Zhou-Yang,et al."The first highly enantioselective lewis base organocatalyzed hydrosilylation of alpha-imino esters".European journal of organic chemistry .4(2010):616-619. |
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来源：中国科学院大学
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