The next-generation sequencing technology: a technology review and future perspective
文献类型：期刊论文
| 作者 | Zhou XiaoGuang1; Ren LuFeng1; Li YunTao2; Zhang Meng1; Yu YuDe2; Yu Jun1 |
| 刊名 | Science china-life sciences
 |
| 出版日期 | 2010 |
| 卷号 | 53期号:1页码:44-57 |
| 关键词 | Genomics Dna sequencing Next generation sequencing technologies Sequencer |
| ISSN号 | 1674-7305 |
| DOI | 10.1007/s11427-010-0023-6 |
| 通讯作者 | Zhou xiaoguang(joezhou@big.ac.cn) |
| 英文摘要 | As one of the most powerful tools in biomedical research, dna sequencing not only has been improving its productivity in an exponential growth rate but also been evolving into a new layout of technological territories toward engineering and physical disciplines over the past three decades. in this technical review, we look into technical characteristics of the next-gen sequencers and provide prospective insights into their future development and applications. we envisage that some of the emerging platforms are capable of supporting the $1000 genome and $100 genome goals if given a few years for technical maturation. we also suggest that scientists from china should play an active role in this campaign that will have profound impact on both scientific research and societal healthcare systems. |
| WOS关键词 | SINGLE DNA-MOLECULES ; POLYMERASE MOLECULES ; CARBON NANOTUBES ; NANOPORE ; GENOME ; IDENTIFICATION ; COLONIES |
| WOS研究方向 | Life Sciences & Biomedicine - Other Topics |
| WOS类目 | Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000276437700007 |
| 出版者 | SCIENCE PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2428023 |
| 专题 | 半导体研究所 |
| 通讯作者 | Zhou XiaoGuang |
| 作者单位 | 1.Chinese Acad Sci, Beijing Inst Genom, Key Lab Genome Sci & Informat, Beijing 100029, Peoples R China 2.Chinese Acad Sci, Inst Semicond, Beijing 100083, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou XiaoGuang,Ren LuFeng,Li YunTao,et al. The next-generation sequencing technology: a technology review and future perspective[J]. Science china-life sciences,2010,53(1):44-57. |
| APA | Zhou XiaoGuang,Ren LuFeng,Li YunTao,Zhang Meng,Yu YuDe,&Yu Jun.(2010).The next-generation sequencing technology: a technology review and future perspective.Science china-life sciences,53(1),44-57. |
| MLA | Zhou XiaoGuang,et al."The next-generation sequencing technology: a technology review and future perspective".Science china-life sciences 53.1(2010):44-57. |
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来源：半导体研究所
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