Implantable cmos neuro-stimulus chip for visual prosthesis
文献类型：期刊论文
| 作者 | Zhang Xu1; Pei WeiHua1; Huang BeiJu1; Wang ShuJing1; Guan Ning1; Guo Kai1; Wang Yu1; Gui Qiang1; Chen Jin1; Wang Kai2 |
| 刊名 | Science china-information sciences
 |
| 出版日期 | 2011-04-01 |
| 卷号 | 54期号:4页码:898-908 |
| 关键词 | Biomedical microelectronics Visual prosthesis Functional electrical stimulation Acute animal experiment Electrical evoked potential (eep) test |
| ISSN号 | 1674-733X |
| DOI | 10.1007/s11432-010-4175-6 |
| 通讯作者 | Zhang xu(zhangxu@semi.ac.cn) |
| 英文摘要 | A prototype chip with 2x2 pixels for implanting in blind patients affected by outer retinal degeneration is presented in this paper. this visual prosthesis chip imitates the degenerated photoreceptor cells, senses the incident light and stimulates the remaining healthy layers of retina or optic nerve. each pixel integrates photodiode and stimulus pulse generator, converting the illumination on the eyes into 3-bit resolution bi-phasic current pulses. on-chip charge cancellation modules are used to discharge each electrode site for tissue safety. the prototype chip is designed and fabricated in 0.18-mu m n-well cmos (complementary metal oxide semiconductor) 1p6m mix-signal process, with a +/- 2.5 v dual voltage supply. the functionality of the fabricated chip is demonstrated on anesthetized rabbits. neural responses in visual cortex are successfully evoked by the neuro-stimulus chip through an on-board trigger interface and flexible electrode. |
| WOS关键词 | RETINAL PROSTHESIS ; STIMULATION ; DEVICE ; BLIND |
| WOS研究方向 | Computer Science |
| WOS类目 | Computer Science, Information Systems |
| 语种 | 英语 |
| WOS记录号 | WOS:000289902100017 |
| 出版者 | SCIENCE CHINA PRESS |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2428178 |
| 专题 | 半导体研究所 |
| 通讯作者 | Zhang Xu |
| 作者单位 | 1.Chinese Acad Sci, Inst Semicond, State Key Lab Integrated Optoelect, Beijing 100083, Peoples R China 2.Peking Univ, Peoples Hosp, Dept Ophthalmol, Beijing 100044, Peoples R China 3.Peking Univ, Dept Epidemiol & Biostat, Hlth Sci Ctr, Beijing 100083, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang Xu,Pei WeiHua,Huang BeiJu,et al. Implantable cmos neuro-stimulus chip for visual prosthesis[J]. Science china-information sciences,2011,54(4):898-908. |
| APA | Zhang Xu.,Pei WeiHua.,Huang BeiJu.,Wang ShuJing.,Guan Ning.,...&Chen HongDa.(2011).Implantable cmos neuro-stimulus chip for visual prosthesis.Science china-information sciences,54(4),898-908. |
| MLA | Zhang Xu,et al."Implantable cmos neuro-stimulus chip for visual prosthesis".Science china-information sciences 54.4(2011):898-908. |
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来源：半导体研究所
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