中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones

文献类型:期刊论文

作者Mao, Beibei ; Qu, Fei ; Zhu, Shuyun ; You, Jinmao
刊名SENSORS AND ACTUATORS B-CHEMICAL
出版日期2016-10-29
英文摘要Herein, utilizing fluorescent Ag nanoclusters (Ag NCs) capped by polyethyleneimine (PEI) with different molecular weights, we constructed a novel Ag NCs-Cu2+ sensing system based on fluorescence turn-on strategy for trace detection of quinolones, including nalidixic acid, cinoxacin, ciprofloxacin/ofloxacin, and moxifloxacin; these were the representatives of four generations of quinolone antibacterial drugs. The fluorescence of Ag NCs could be efficiently quenched by Cu2+, while with the addition of quinolones, the fluorescence of this system recovered rapidly. This protocol exhibited excellent sensitivities to these five quinolones. For instance, the linear ranges were from 1 to 100 nM for nalidixic acid with limit of detection (LOD) 0.47 nM, from 1 to 80 nM for cinoxacin with LOD 0.43 nM, from 0.1 to 120 nM for ciprofloxacin with LOD 38 pM, from 0.1 to 80 nM for ofloxacin with LOD 49 pM, and from 0.1 to 120 nM for moxifloxacin with LOD 48 pM, respectively, revealing that this approach showed low detection limits and wide linear ranges. Benefiting from the high sensitivity, the satisfactory recoveries were obtained for trace detection of quinolones in real samples, such as tablets, human urine and serum. (C) 2016 Elsevier B.V. All rights reserved.
源URL[http://ir.nwipb.ac.cn/handle/363003/6479]  
专题西北高原生物研究所_中国科学院西北高原生物研究所
推荐引用方式
GB/T 7714
Mao, Beibei,Qu, Fei,Zhu, Shuyun,et al. Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones[J]. SENSORS AND ACTUATORS B-CHEMICAL,2016.
APA Mao, Beibei,Qu, Fei,Zhu, Shuyun,&You, Jinmao.(2016).Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones.SENSORS AND ACTUATORS B-CHEMICAL.
MLA Mao, Beibei,et al."Fluorescence turn-on strategy based on silver nanoclusters-Cu2+ system for trace detection of quinolones".SENSORS AND ACTUATORS B-CHEMICAL (2016).

入库方式: OAI收割

来源:西北高原生物研究所

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