Hepatoprotective and toxic characteristics of the whole herb of traditional Tibetan folk medicine Swertia mussotii Franch.
文献类型：期刊论文
| 作者 | Lv, Ping ; Wei, Lixin ; Du, Yuzhi ; Yang, Hongxia ; Peng, Min |
| 刊名 | JOURNAL OF MEDICINAL PLANTS RESEARCH
 ; Lv, P; Wei, LX; Du, YZ; Yang, HX; Peng, M.Hepatoprotective and toxic characteristics of the whole herb of traditional Tibetan folk medicine Swertia mussotii Franch.,JOURNAL OF MEDICINAL PLANTS RESEARCH,2010,4(8):706-709
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| 出版日期 | 2010-04-18 |
| 英文摘要 | Swertia mussotii Franch. (SM) (Gentianaceae) was a traditional Tibetan folk herb for hepatitis in the Qinghai-Tibet plateau areas. For understanding the hepatoprotection and toxicity characteristics of Swertia mussotii Franch., the whole plant of Swertia mussotii was extracted by water (SME-b) and 75% ethanol (SME-a); then, SME-a was dissolved with water, the supernatant was SME-c, and the sedimentation was SME-d. 17.76% SME-a, 14.48% SME-b, 10.13% SME-c, and 4.35% SME-d were extracted from Swertia mussotii. These four extracts were evaluated with acute toxicity and hepatoprotective effect on CCl(4)-induced acute liver damage in mice. The toxic material mainly reside in SME-c and SME-a. The hepatoprotective materials were in SME-a, SME-c and SME-d, while SME-b had no hepatoprotective activities. So, SME-a and SME-c had both the hepatoprotection and toxicity characteristics; SME-b had no toxicity or the hepatoprotection characteristics; only SME-d was hepatoprotective function without toxicity, which could be a good candidate for new drug healing the live disorder.; Swertia mussotii Franch. (SM) (Gentianaceae) was a traditional Tibetan folk herb for hepatitis in the Qinghai-Tibet plateau areas. For understanding the hepatoprotection and toxicity characteristics of Swertia mussotii Franch., the whole plant of Swertia mussotii was extracted by water (SME-b) and 75% ethanol (SME-a); then, SME-a was dissolved with water, the supernatant was SME-c, and the sedimentation was SME-d. 17.76% SME-a, 14.48% SME-b, 10.13% SME-c, and 4.35% SME-d were extracted from Swertia mussotii. These four extracts were evaluated with acute toxicity and hepatoprotective effect on CCl(4)-induced acute liver damage in mice. The toxic material mainly reside in SME-c and SME-a. The hepatoprotective materials were in SME-a, SME-c and SME-d, while SME-b had no hepatoprotective activities. So, SME-a and SME-c had both the hepatoprotection and toxicity characteristics; SME-b had no toxicity or the hepatoprotection characteristics; only SME-d was hepatoprotective function without toxicity, which could be a good candidate for new drug healing the live disorder. |
| 源URL | [http://ir.nwipb.ac.cn//handle/363003/1720]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Lv, Ping,Wei, Lixin,Du, Yuzhi,et al. Hepatoprotective and toxic characteristics of the whole herb of traditional Tibetan folk medicine Swertia mussotii Franch.[J]. JOURNAL OF MEDICINAL PLANTS RESEARCH, Lv, P; Wei, LX; Du, YZ; Yang, HX; Peng, M.Hepatoprotective and toxic characteristics of the whole herb of traditional Tibetan folk medicine Swertia mussotii Franch.,JOURNAL OF MEDICINAL PLANTS RESEARCH,2010,4(8):706-709,2010. |
| APA | Lv, Ping,Wei, Lixin,Du, Yuzhi,Yang, Hongxia,&Peng, Min.(2010).Hepatoprotective and toxic characteristics of the whole herb of traditional Tibetan folk medicine Swertia mussotii Franch..JOURNAL OF MEDICINAL PLANTS RESEARCH. |
| MLA | Lv, Ping,et al."Hepatoprotective and toxic characteristics of the whole herb of traditional Tibetan folk medicine Swertia mussotii Franch.".JOURNAL OF MEDICINAL PLANTS RESEARCH (2010). |
入库方式： OAI收割
来源：西北高原生物研究所
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