EFFECT OF ARGIPRESSIN AND ITS RELATED-COMPOUNDS ON CORTICOTROPIN RELEASING HORMONE CONTENTS IN HYPOTHALAMUS OF RATS
文献类型：期刊论文
| 作者 | DU, JZ; YOU, ZB |
| 刊名 | ACTA PHARMACOLOGICA SINICA
 |
| 出版日期 | 1991-03-01 |
| 卷号 | 12期号:2页码:164-166 |
| 关键词 | Argipressin Peptides Corticotropin Releasing Hormone Corticosterone Median Eminence |
| ISSN号 | 0253-9756 |
| 文献子类 | Article |
| 英文摘要 | The paper mainly stresses on the effect of argipressin (Arg), 2-destyrosyl-3-desphenyl-alanyl-9-desglycyl-9-desglycyl-amide-Arg (Arg4-8), [1-deaminopenicillamine, 2-(o-methyl)tyrosine]-Arg (DPArg) and Arg antiserum on corticotropin releasing hormone (CRH) contents in median eminence (ME) and the level of plasma corticosterone after injected into the third ventricle of rats. The results show: 1) the CRH contents in ME significantly reduced with icv 100, 200, and 800 ng of Arg; 2) 100 ng of Arg4-8 and Arg antiserum (2-mu-l, 1:1 diluted with 0.9% saline) increased CRH contents in ME and enhanced plasma corticosterone; 3) DPArg had no effect on CRH level but blocked the inhibitory role of Arg on central CRH. These results suggest that Arg acts as an inhibitory factor in regulating central CRH level and V1 receptor is involved. |
| WOS关键词 | ARGININE VASOPRESSIN ; SECRETION ; CATECHOLAMINES ; NEURONS ; CELLS |
| WOS研究方向 | Chemistry ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:A1991FB87500015 |
| 出版者 | ACTA PHARMACOLOGICA SINICA |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/13267]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 通讯作者 | YOU, ZB |
| 推荐引用方式 GB/T 7714 | DU, JZ,YOU, ZB. EFFECT OF ARGIPRESSIN AND ITS RELATED-COMPOUNDS ON CORTICOTROPIN RELEASING HORMONE CONTENTS IN HYPOTHALAMUS OF RATS[J]. ACTA PHARMACOLOGICA SINICA,1991,12(2):164-166. |
| APA | DU, JZ,&YOU, ZB.(1991).EFFECT OF ARGIPRESSIN AND ITS RELATED-COMPOUNDS ON CORTICOTROPIN RELEASING HORMONE CONTENTS IN HYPOTHALAMUS OF RATS.ACTA PHARMACOLOGICA SINICA,12(2),164-166. |
| MLA | DU, JZ,et al."EFFECT OF ARGIPRESSIN AND ITS RELATED-COMPOUNDS ON CORTICOTROPIN RELEASING HORMONE CONTENTS IN HYPOTHALAMUS OF RATS".ACTA PHARMACOLOGICA SINICA 12.2(1991):164-166. |
入库方式： OAI收割
来源：西北高原生物研究所
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