Protection against vascular endothelial dysfunction by polyphenols in sea buckthorn berries in rats with hyperlipidemia
文献类型：期刊论文
| 作者 | Yang, Fang ; Suo, Yourui ; Chen, Dongli ; Tong, Li |
| 刊名 | BIOSCIENCE TRENDS
 |
| 出版日期 | 2016-06-01 |
| 英文摘要 | Chronic hyperlipemia increases the incidence of vascular endothelial dysfunction and can even induce cardiovascular disease. Sea buckthorn contains a host of bioactives such as flavonoids and polyphenols that can prevent the development of cardiovascular disease. The current study isolated active ingredients, polyphenols, from sea buckthorn berries (SVP) and orally administered SVP at a dose of 7-28 mg/kg. This treatment significantly reduced serum lipids, it enhanced the activity of antioxidant enzymes, and it decreased the level of serum TNF-alpha and IL-6. SVP also alleviate vascular impairment by decreasing the expression of eNOS, ICAM-1, and LOX-1 mRNA and proteins in aortas of rats with hyperlipidemia. Based on these findings, SVP has antioxidant action and it protects endothelium. |
| 源URL | [http://ir.nwipb.ac.cn/handle/363003/6469]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Yang, Fang,Suo, Yourui,Chen, Dongli,et al. Protection against vascular endothelial dysfunction by polyphenols in sea buckthorn berries in rats with hyperlipidemia[J]. BIOSCIENCE TRENDS,2016. |
| APA | Yang, Fang,Suo, Yourui,Chen, Dongli,&Tong, Li.(2016).Protection against vascular endothelial dysfunction by polyphenols in sea buckthorn berries in rats with hyperlipidemia.BIOSCIENCE TRENDS. |
| MLA | Yang, Fang,et al."Protection against vascular endothelial dysfunction by polyphenols in sea buckthorn berries in rats with hyperlipidemia".BIOSCIENCE TRENDS (2016). |
入库方式： OAI收割
来源：西北高原生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。