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Cell-imprinted polydimethylsiloxane for the selective cell adhesion

文献类型：期刊论文

作者Zhang, Yukui1; Liu, Lukuan1,2,3; Yang, Kaiguang1; Dai, Zhongpeng1; Liang, Zhen1; Zhang, Lihua1; Peng, Xiaojun3
刊名CHINESE CHEMICAL LETTERS
出版日期2019-03-01
卷号30期号:3页码:672-675
ISSN号1001-8417
关键词Cell adhesion Aptamer Cell imprinting Hierarchical structures Click chemistry
DOI10.1016/j.cclet.2018.11.006
通讯作者Zhang, Lihua(lihuazhang@dicp.ac.cn)
英文摘要Cell adhesion is the basis for some cell isolation methods, and is influenced by both of the biochemical and topographic characteristics of the substrates. Herein, based on cell imprinting and click chemistry, we have developed a cell-imprinted polydimethylsiloxane (PDMS) with aptamer functionalization (APT-CIS). The atom force microscopic analysis results showed that the hierarchical structure matching well with the target cells is successfully introduced on the surface of the APT-CIS. By using the synergistic effects of hierarchical structure and aptamer affinity, the APT-CIS was successfully used for the selective cell adhesion, and 93.9% +/- 0.8% of the captured cells could then be released. Thus, the APT-CIS holds promise in selective cell isolation and sorting fields. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
WOS关键词CANCER-CELLS ; APTAMER ; RECOGNITION ; CAPTURE
资助项目National Key Research and Development Program[2016YFA0501401] ; National Natural Science Foundation of China[21575143] ; National Natural Science Foundation of China[91543201] ; CAS Key Project in Frontier Science[QYZDY-SSW-SLH017]
WOS研究方向Chemistry
语种英语
出版者ELSEVIER SCIENCE INC
WOS记录号WOS:000462106900031
资助机构National Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; National Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; National Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science ; National Key Research and Development Program ; National Key Research and Development Program ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; CAS Key Project in Frontier Science ; CAS Key Project in Frontier Science
源URL[http://cas-ir.dicp.ac.cn/handle/321008/165742]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者Zhang, Lihua
作者单位1.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
3.Dalian Univ Technol, State Key Lab Fine Chem, Dalian 116024, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Yukui,Liu, Lukuan,Yang, Kaiguang,et al. Cell-imprinted polydimethylsiloxane for the selective cell adhesion[J]. CHINESE CHEMICAL LETTERS,2019,30(3):672-675.
APA Zhang, Yukui.,Liu, Lukuan.,Yang, Kaiguang.,Dai, Zhongpeng.,Liang, Zhen.,...&Peng, Xiaojun.(2019).Cell-imprinted polydimethylsiloxane for the selective cell adhesion.CHINESE CHEMICAL LETTERS,30(3),672-675.
MLA Zhang, Yukui,et al."Cell-imprinted polydimethylsiloxane for the selective cell adhesion".CHINESE CHEMICAL LETTERS 30.3(2019):672-675.

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来源：大连化学物理研究所

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