中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A self-assembly/disassembly two-photo ratiometric fluorogenic probe for bacteria imaging

文献类型:期刊论文

作者Long, Shuangshuang1,2; Qiao, Qinglong2; Miao, Lu2; Xu, Zhaochao2
刊名CHINESE CHEMICAL LETTERS
出版日期2019-03-01
卷号30期号:3页码:573-576
ISSN号1001-8417
关键词Fluorogenic probe Bacteria Self-assembly Imidazolium Pyrene
DOI10.1016/j.cclet.2018.11.031
通讯作者Xu, Zhaochao(zcxu@dicp.ac.cn)
英文摘要Fluorescence imaging has facilitated fluorescent probes to analyze the subcellular localization and dynamics of biological targets. In this paper, we reported a fluorogenic probe for bacteria imaging. The probe was an imidazolium-derived pyrene compound, which self-assembled to form nano-particles and the pyrene fluorescence was quenched by the aggregation effects. When the self-assembly nanoparticles interacted with anionic bacteria surfaces, synergistic effects of electrostatic interaction and hydrophobic force caused competing binding between bacteria surfaces and imidazoliums. This binding resulted in the disassembly of the aggregates to give fluorescence turn-on signal. Meanwhile, the probe bound bacteria surfaces and displayed both pyrene-excimer and pyrene-monomer fluorescence, which gave ratiometric signal. Then, fluorescent labeling by the probe enabled the two-photo ratiometric imaging of bacteria. (C) 2018 Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. Published by Elsevier B.V. All rights reserved.
WOS关键词IDENTIFICATION ; FLUORESCENCE ; PYRENE ; WATER ; ATP
资助项目National Natural Science Foundation of China[21878286] ; National Natural Science Foundation of China[21502189] ; DICP[DMT0201603] ; DICP[TMSR201601]
WOS研究方向Chemistry
语种英语
出版者ELSEVIER SCIENCE INC
WOS记录号WOS:000462106900010
资助机构National Natural Science Foundation of China ; National Natural Science Foundation of China ; DICP ; DICP ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; DICP ; DICP ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; DICP ; DICP ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; DICP ; DICP
源URL[http://cas-ir.dicp.ac.cn/handle/321008/165760]  
专题大连化学物理研究所_中国科学院大连化学物理研究所
通讯作者Xu, Zhaochao
作者单位1.Univ Chinese Acad Sci, Beijing 100039, Peoples R China
2.Chinese Acad Sci, Dalian Inst Chem Phys, CAS Key Lab Separat Sci Analyt Chem, Dalian 116023, Peoples R China
推荐引用方式
GB/T 7714
Long, Shuangshuang,Qiao, Qinglong,Miao, Lu,et al. A self-assembly/disassembly two-photo ratiometric fluorogenic probe for bacteria imaging[J]. CHINESE CHEMICAL LETTERS,2019,30(3):573-576.
APA Long, Shuangshuang,Qiao, Qinglong,Miao, Lu,&Xu, Zhaochao.(2019).A self-assembly/disassembly two-photo ratiometric fluorogenic probe for bacteria imaging.CHINESE CHEMICAL LETTERS,30(3),573-576.
MLA Long, Shuangshuang,et al."A self-assembly/disassembly two-photo ratiometric fluorogenic probe for bacteria imaging".CHINESE CHEMICAL LETTERS 30.3(2019):573-576.

入库方式: OAI收割

来源:大连化学物理研究所

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