Rapid Identification of Bacteria by Membrane-Responsive Aggregation of a Pyrene Derivative
文献类型：期刊论文
| 作者 | Long, Shuangshuang2,3; Miao, Lu2; Li, Ruihua4; Deng, Fei2,3; Qaao, Qinglong2; Liu, Xiaogang5; Yan, Aixin1; Xu, Zhaochao2 |
| 刊名 | ACS SENSORS
 |
| 出版日期 | 2019-02-01 |
| 卷号 | 4期号:2页码:281-285 |
| ISSN号 | 2379-3694 |
| 关键词 | bacteria identification multidrug resistant pyrene derivative aggregation rapid identification |
| DOI | 10.1021/acssensors.8b01466 |
| 通讯作者 | Xu, Zhaochao(zcxu@dicp.ac.cn) |
| 英文摘要 | An imidazolium-derived pyrene aggregation was developed to rapidly identify and quantify different bacteria species. When the nonemissive aggregates bound to the anionic bacteria surface, the sensor disassembled to turn on significant fluorescence. At the same time, ratiometric signals between pyrene monomer and excimer emission were controlled by different interactions with various bacteria surfaces. The resulted different fluorescent emission profiles then were obtained as fingerprints for various bacterial species. By converting emission profiles directly into output signals of two channels, fluorescence increase and ratiometric change, a two-dimensional analysis map was generated for bacteria identification. We demonstrated that our sensor rapidly identified 10 species of bacteria and 14 clinical isolated multidrug-resistant bacteria, and we determined their staining properties (Gram-positive or Gram-negative). |
| WOS关键词 | SENSOR ARRAY ; DISCRIMINATION ; NANOPARTICLES ; MECHANISMS ; MICELLES ; CHARGES ; POLYMER |
| 资助项目 | NSFC[21878286] ; NSFC[21502189] ; DICP[DMTO201603] ; DICP[TMSR201601] |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics |
| 语种 | 英语 |
| 出版者 | AMER CHEMICAL SOC |
| WOS记录号 | WOS:000459836400003 |
| 资助机构 | NSFC ; NSFC ; DICP ; DICP ; NSFC ; NSFC ; DICP ; DICP ; NSFC ; NSFC ; DICP ; DICP ; NSFC ; NSFC ; DICP ; DICP |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/165822]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Xu, Zhaochao |
| 作者单位 | 1.Univ Hong Kong, Sch Biol Sci, Hong Kong, Peoples R China 2.Chinese Acad Sci, CAS Key Lab Separat Sci Analyt Chem, Dalian Inst Chem Phys, Dalian 116023, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 4.Dalian Med Univ, Affiliated Hosp 2, Dalian 116023, Peoples R China 5.Singapore Univ Technol & Design, Singapore 487372, Singapore |
| 推荐引用方式 GB/T 7714 | Long, Shuangshuang,Miao, Lu,Li, Ruihua,et al. Rapid Identification of Bacteria by Membrane-Responsive Aggregation of a Pyrene Derivative[J]. ACS SENSORS,2019,4(2):281-285. |
| APA | Long, Shuangshuang.,Miao, Lu.,Li, Ruihua.,Deng, Fei.,Qaao, Qinglong.,...&Xu, Zhaochao.(2019).Rapid Identification of Bacteria by Membrane-Responsive Aggregation of a Pyrene Derivative.ACS SENSORS,4(2),281-285. |
| MLA | Long, Shuangshuang,et al."Rapid Identification of Bacteria by Membrane-Responsive Aggregation of a Pyrene Derivative".ACS SENSORS 4.2(2019):281-285. |
入库方式： OAI收割
来源：大连化学物理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。