Rhodium(III)-Catalyzed Enantioselective Coupling of Indoles and 7-Azabenzonorbornadienes by C-H Activation/Desymmetrization
文献类型：期刊论文
| 作者 | Li, Xingwei1,2; Yang, Xifa2; Zheng, Guangfan1 |
| 刊名 | ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
 |
| 出版日期 | 2019-01-02 |
| 卷号 | 58期号:1页码:322-326 |
| 关键词 | C-H activation desymmetrization heterocycles rhodium synthetic methods |
| ISSN号 | 1433-7851 |
| DOI | 10.1002/anie.201811998 |
| 通讯作者 | Zheng, Guangfan(zhenggf@snnu.edu.cn) ; Li, Xingwei(lixw@snnu.edu.cn) |
| 英文摘要 | Chiral rhodium(III) cyclopentadienyl catalysts ((CpRhIII)-Rh-X) play significant roles in asymmetric arene C-H activation. Rh/Ir-catalyzed couplings of arenes and strained rings have been well-studied, but they have been limited to racemic systems. Reported in this work is the (CpRhIII)-Rh-x/AgSbF6-catalyzed enantioselective desymmetrizative C-C coupling of N-pyrimidylindoles and 7-azabenzonorbornadienes with high efficiency and enantioselectivity. The role of AgSbF6 has been established by mechanistic studies. AgSbF6 enhances the catalytic activity by suppressing the C3-H activation of the indoles, activation which would otherwise lead to catalytically inactive species. |
| WOS关键词 | RING-OPENING REACTIONS ; CHIRAL CYCLOPENTADIENYL LIGANDS ; BOND-FORMING REACTIONS ; HETEROBICYCLIC ALKENES ; ACTIVATION ; ARENES ; CATALYSTS ; AZABENZONORBORNADIENES ; HYDROARYLATIONS ; COMPLEXES |
| 资助项目 | NSFC[21525208] ; NSFC[21472186] ; SNNU |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000455818400051 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 资助机构 | NSFC ; NSFC ; SNNU ; SNNU ; NSFC ; NSFC ; SNNU ; SNNU ; NSFC ; NSFC ; SNNU ; SNNU ; NSFC ; NSFC ; SNNU ; SNNU |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/166174]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Li, Xingwei; Zheng, Guangfan |
| 作者单位 | 1.Shaanxi Normal Univ SNNU, Sch Chem & Chem Engn, MOE, Key Lab Appl Surface & Colloid Chem, Xian 710062, Shaanxi, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian 116023, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Xingwei,Yang, Xifa,Zheng, Guangfan. Rhodium(III)-Catalyzed Enantioselective Coupling of Indoles and 7-Azabenzonorbornadienes by C-H Activation/Desymmetrization[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,2019,58(1):322-326. |
| APA | Li, Xingwei,Yang, Xifa,&Zheng, Guangfan.(2019).Rhodium(III)-Catalyzed Enantioselective Coupling of Indoles and 7-Azabenzonorbornadienes by C-H Activation/Desymmetrization.ANGEWANDTE CHEMIE-INTERNATIONAL EDITION,58(1),322-326. |
| MLA | Li, Xingwei,et al."Rhodium(III)-Catalyzed Enantioselective Coupling of Indoles and 7-Azabenzonorbornadienes by C-H Activation/Desymmetrization".ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 58.1(2019):322-326. |
入库方式： OAI收割
来源：大连化学物理研究所
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