Barriers and opportunities in bio-based production of hydrocarbons
文献类型：期刊论文
| 作者 | Zhou, Yongjin J.2,3,4; Kerkhoven, Eduard J.4; Nielsen, Jens1,4,5 |
| 刊名 | NATURE ENERGY
 |
| 出版日期 | 2018-11-01 |
| 卷号 | 3期号:11页码:925-935 |
| ISSN号 | 2058-7546 |
| DOI | 10.1038/s41560-018-0197-x |
| 通讯作者 | Nielsen, Jens(nielsenj@chalmers.se) |
| 英文摘要 | Global climate change caused by the accumulation of greenhouse gases (GHGs) has caused concerns regarding the continued reliance on fossil fuels as our primary energy source. Hydrocarbons produced from biomass using microbial fermentation processes can serve as high-quality liquid transportation fuels and may contribute to a reduction in GHG emissions. Here, we discuss the barriers and opportunities for bio-based production of hydrocarbons to be used as diesel and jet fuels and review recent advances in engineering microbes for production of these chemicals. There are two main challenges associated with establishing bio-based hydrocarbon production from cheap feedstocks; lowering the cost of developing efficient and robust microbial cell factories and establishing more efficient routes for biomass hydrolysis to sugars for fermentation. We discuss how to develop novel systems and synthetic biology tools that can enable faster and cheaper construction of microbial cell factories and thereby address the first challenge, as well as recent advances in biomass processing that will likely lead to overcoming the second challenge in the near future. |
| WOS关键词 | YEAST YARROWIA-LIPOLYTICA ; FATTY-ACID SYNTHASES ; ESCHERICHIA-COLI ; SACCHAROMYCES-CEREVISIAE ; METHYLOBACTERIUM-EXTORQUENS ; EXTRACTIVE FERMENTATION ; MICROBIAL BIOSYNTHESIS ; 1-ALKENE BIOSYNTHESIS ; ISOPRENE PRODUCTION ; ALKANE PRODUCTION |
| 资助项目 | National Natural Science Foundation of China[31700082] ; DMTO research grant from Dalian Institute of Chemicals Physics, CAS[DICP DMTO201701] ; Novo Nordisk Foundation ; Knut and Alice Wallenberg Foundation ; US Department of Energy, Office of Science, Office of Biological and Environmental Research, Genomic Science program[DE-SC0008744] ; Horizon2020 via the CHASSY project[720824] ; Aforsk Foundation |
| WOS研究方向 | Energy & Fuels ; Materials Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000449518300011 |
| 出版者 | NATURE PUBLISHING GROUP |
| 资助机构 | National Natural Science Foundation of China ; National Natural Science Foundation of China ; DMTO research grant from Dalian Institute of Chemicals Physics, CAS ; DMTO research grant from Dalian Institute of Chemicals Physics, CAS ; Novo Nordisk Foundation ; Novo Nordisk Foundation ; Knut and Alice Wallenberg Foundation ; Knut and Alice Wallenberg Foundation ; US Department of Energy, Office of Science, Office of Biological and Environmental Research, Genomic Science program ; US Department of Energy, Office of Science, Office of Biological and Environmental Research, Genomic Science program ; Horizon2020 via the CHASSY project ; Horizon2020 via the CHASSY project ; Aforsk Foundation ; Aforsk Foundation ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; DMTO research grant from Dalian Institute of Chemicals Physics, CAS ; DMTO research grant from Dalian Institute of Chemicals Physics, CAS ; Novo Nordisk Foundation ; Novo Nordisk Foundation ; Knut and Alice Wallenberg Foundation ; Knut and Alice Wallenberg Foundation ; US Department of Energy, Office of Science, Office of Biological and Environmental Research, Genomic Science program ; US Department of Energy, Office of Science, Office of Biological and Environmental Research, Genomic Science program ; Horizon2020 via the CHASSY project ; Horizon2020 via the CHASSY project ; Aforsk Foundation ; Aforsk Foundation ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; DMTO research grant from Dalian Institute of Chemicals Physics, CAS ; DMTO research grant from Dalian Institute of Chemicals Physics, CAS ; Novo Nordisk Foundation ; Novo Nordisk Foundation ; Knut and Alice Wallenberg Foundation ; Knut and Alice Wallenberg Foundation ; US Department of Energy, Office of Science, Office of Biological and Environmental Research, Genomic Science program ; US Department of Energy, Office of Science, Office of Biological and Environmental Research, Genomic Science program ; Horizon2020 via the CHASSY project ; Horizon2020 via the CHASSY project ; Aforsk Foundation ; Aforsk Foundation ; National Natural Science Foundation of China ; National Natural Science Foundation of China ; DMTO research grant from Dalian Institute of Chemicals Physics, CAS ; DMTO research grant from Dalian Institute of Chemicals Physics, CAS ; Novo Nordisk Foundation ; Novo Nordisk Foundation ; Knut and Alice Wallenberg Foundation ; Knut and Alice Wallenberg Foundation ; US Department of Energy, Office of Science, Office of Biological and Environmental Research, Genomic Science program ; US Department of Energy, Office of Science, Office of Biological and Environmental Research, Genomic Science program ; Horizon2020 via the CHASSY project ; Horizon2020 via the CHASSY project ; Aforsk Foundation ; Aforsk Foundation |
| 源URL | [http://cas-ir.dicp.ac.cn/handle/321008/166730]  |
| 专题 | 大连化学物理研究所_中国科学院大连化学物理研究所 |
| 通讯作者 | Nielsen, Jens |
| 作者单位 | 1.Tech Univ Denmark, Novo Nordisk Fdn Ctr Biosustainabil, Lyngby, Denmark 2.Chinese Acad Sci, Dalian Inst Chem Phys, Key Lab Separat Sci Analyt Chem, Dalian, Peoples R China 3.Chinese Acad Sci, Dalian Inst Chem Phys, Div Biotechnol, Dalian, Peoples R China 4.Chalmers Univ Technol, Dept Biol & Biol Engn, Gothenburg, Sweden 5.Beijing Univ Chem Technol, Beijing Adv Innovat Ctr Soft Matter Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhou, Yongjin J.,Kerkhoven, Eduard J.,Nielsen, Jens. Barriers and opportunities in bio-based production of hydrocarbons[J]. NATURE ENERGY,2018,3(11):925-935. |
| APA | Zhou, Yongjin J.,Kerkhoven, Eduard J.,&Nielsen, Jens.(2018).Barriers and opportunities in bio-based production of hydrocarbons.NATURE ENERGY,3(11),925-935. |
| MLA | Zhou, Yongjin J.,et al."Barriers and opportunities in bio-based production of hydrocarbons".NATURE ENERGY 3.11(2018):925-935. |
入库方式： OAI收割
来源：大连化学物理研究所
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